Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 18/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4644262 | 1.00 | ADRB3 (0.42) | ADRB3ADRB2ADRB1NR1I2HPGD | |
| Trifluoroacetic Acid SCHEMBL4642020 | 0.97 | ADRB3 (0.41) | ADRB3ADRB2ADRB1NR1I2HPGD | |
| SCHEMBL4642267 | 0.89 | ADRB3 (0.40) | ADRB3ADRB2ADRB1NR1I2HPGD | |
| SCHEMBL4644125 | 0.89 | ADRB3 (0.40) | ADRB3ADRB2ADRB1NR1I2HPGD | |
| SCHEMBL4644258 | 0.89 | ADRB3 (0.42) | ADRB3ADRB2ADRB1NR1I2HPGD | |
| SCHEMBL4639638 | 0.89 | ADRB3 (0.42) | ADRB3ADRB2ADRB1NR1I2HPGD | |
| SCHEMBL4917477 | 0.89 | ADRB3 (0.42) | ADRB3ADRB2ADRB1NR1I2HPGD | |
| SCHEMBL4648541 | 0.88 | ADRB3 (0.41) | ADRB3ADRB2ADRB1NR1I2HPGD | |
| SCHEMBL4640331 | 0.88 | ADRB3 (0.41) | ADRB3ADRB2ADRB1NR1I2HPGD | |
| SCHEMBL4642662 | 0.88 | ADRB3 (0.41) | ADRB3ADRB2ADRB1NR1I2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1943229-A1 | BENZIMIDAZOLE DERIVATIVES FOR USE AS BETA-3 RECEPTOR AGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-07-16 | — | — | EP | claimed |
| WO-2007048842-A1 | BENZIMIDAZOLE DERIVATIVES FOR USE AS BETA-3 RECEPTOR AGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-05-03 | — | — | WO | claimed |
| EP-1943229-A1 | BENZIMIDAZOLE DERIVATIVES FOR USE AS BETA-3 RECEPTOR AGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007048842-A1 | BENZIMIDAZOLE DERIVATIVES FOR USE AS BETA-3 RECEPTOR AGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-05-03 | — | — | WO | disclosed |