Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 6/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 9/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4645527 | 1.00 | ADRB3 (0.41) | ADRB3NR1I2HPGDADRB2ADRB1 | |
| SCHEMBL4640331 | 0.97 | ADRB3 (0.41) | ADRB3NR1I2HPGDADRB2ADRB1 | |
| SCHEMBL4642662 | 0.97 | ADRB3 (0.41) | ADRB3NR1I2HPGDADRB2ADRB1 | |
| Trifluoroacetic Acid SCHEMBL4639804 | 0.94 | ADRB3 (0.41) | ADRB3NR1I2HPGDADRB2ADRB1 | |
| SCHEMBL4649033 | 0.92 | ADRB3 (0.42) | ADRB3NR1I2HPGDADRB2ADRB1 | |
| SCHEMBL4649135 | 0.92 | ADRB3 (0.42) | ADRB3NR1I2HPGDADRB2ADRB1 | |
| SCHEMBL4642404 | 0.92 | ADRB3 (0.41) | ADRB3NR1I2HPGDADRB2ADRB1 | |
| SCHEMBL4641939 | 0.92 | ADRB3 (0.41) | ADRB3NR1I2HPGDADRB2ADRB1 | |
| SCHEMBL14185294 | 0.91 | ADRB3 (0.44) | ADRB3NR1I2HPGDADRB2ADRB1 | |
| SCHEMBL4645522 | 0.89 | ADRB3 (0.41) | ADRB3NR1I2HPGDADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1943229-A1 | BENZIMIDAZOLE DERIVATIVES FOR USE AS BETA-3 RECEPTOR AGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-07-16 | — | — | EP | claimed |
| WO-2007048842-A1 | BENZIMIDAZOLE DERIVATIVES FOR USE AS BETA-3 RECEPTOR AGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-05-03 | — | — | WO | claimed |
| EP-1943229-A1 | BENZIMIDAZOLE DERIVATIVES FOR USE AS BETA-3 RECEPTOR AGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007048842-A1 | BENZIMIDAZOLE DERIVATIVES FOR USE AS BETA-3 RECEPTOR AGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-05-03 | — | — | WO | disclosed |