⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL220683 | 0.68 | — | — | |
| SCHEMBL3457562 | 0.67 | — | — | |
| SCHEMBL1484260 | 0.64 | ALDH1A1 (0.33) | — | |
| SCHEMBL449522 | 0.57 | — | — | |
| SCHEMBL17420980 | 0.57 | — | — | |
| SCHEMBL1484172 | 0.57 | — | — | |
| SCHEMBL4583976 | 0.55 | — | — | |
| SCHEMBL206995 | 0.55 | — | — | |
| SCHEMBL71471 | 0.53 | — | — | |
| SCHEMBL190851 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951704-A1 | 1,3-DIHYDRO-BENZIMIDAZOL-2-YLIDENE AMINES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Tibotec Pharmaceuticals Ltd. (IE) | 2008-08-06 | — | — | EP | disclosed |
| WO-2006097534-A1 | 1,3-DIHYDRO-BENZIMIDAZOL-2-YLIDENE AMINES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | TIBOTEC PHARMACEUTICALS LTD (IE) | 2006-09-21 | — | — | WO | disclosed |