Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 20/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4506638 | 0.81 | PTGDR (1.00) | PTGDR | |
| SCHEMBL4494350 | 0.80 | PTGDR (1.00) | PTGDR | |
| SCHEMBL4496591 | 0.80 | PTGDR (0.70) | PTGDR | |
| SCHEMBL9911090 | 0.79 | PTGDR (0.79) | PTGDR | |
| SCHEMBL4619763 | 0.77 | PTGDR (0.68) | PTGDR | |
| SCHEMBL10476013 | 0.77 | PTGDR (0.69) | PTGDR | |
| SCHEMBL4640354 | 0.76 | PTGDR (0.72) | PTGDR | |
| SCHEMBL15757063 | 0.76 | NUDT1 (0.57) | PTGDR | |
| SCHEMBL4492174 | 0.76 | PTGDR (1.00) | PTGDR | |
| SCHEMBL4503850 | 0.75 | PTGDR (0.79) | PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891019-A2 | 2,6-SUBSTITUTED-4-MONOSUBSTITUTEDAMINO-PYRIMIDINE AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | Aventis Pharmaceuticals Inc. (US) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006044732-A2 | 2, 6-SUBSTITUTED-4-MONOSUBSTITUTEDAMINO-PYRIMIDINE AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | AVENTIS PHARMACEUTICALS INC. (US) | 2006-04-27 | — | — | WO | disclosed |