⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL790697 | 0.97 | — | — | |
| SCHEMBL295959 | 0.81 | LMNA (0.39) | — | |
| SCHEMBL5859882 | 0.76 | LMNA (0.31) | — | |
| SCHEMBL17613261 | 0.76 | — | — | |
| SCHEMBL308932 | 0.76 | — | — | |
| SCHEMBL5859665 | 0.76 | LMNA (0.31) | — | |
| SCHEMBL4640391 | 0.74 | HDAC2 (0.32) | — | |
| SCHEMBL536314 | 0.74 | — | — | |
| SCHEMBL3164534 | 0.74 | EPHX1 (0.32) | — | |
| SCHEMBL6722236 | 0.74 | EPHX1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1437139-B1 | Method for protection against genotoxic mutagenesis | ARCH DEV CORP (US) | 2008-07-16 | — | — | EP | disclosed |
| EP-1437139-A2 | Method for protection against genotoxic mutagenesis | ARCH DEVELOPMENT CORPORATION (US) | 2004-07-14 | — | — | EP | disclosed |
| EP-0764027-A4 | METHOD FOR PROTECTION AGAINST GENOTOXIC MUTAGENESIS | ARCH DEV CORP (US) | 1998-04-22 | — | — | EP | disclosed |
| EP-0764027-A1 | METHOD FOR PROTECTION AGAINST GENOTOXIC MUTAGENESIS | ARCH DEVELOPMENT CORPORATION (US) | 1997-03-26 | — | — | EP | disclosed |
| US-5567686-A | Method for protection against genotoxic mutagenesis | ARCH DEVELOPMENT CORPORATION (US) | 1996-10-22 | — | — | US | disclosed |
| WO-1995007700-A1 | METHOD FOR PROTECTION AGAINST GENOTOXIC MUTAGENESIS | ARCH DEVELOPMENT CORPORATION (US) | 1995-03-23 | — | — | WO | disclosed |