Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.94 |
| ▸ | CA12 | O43570 | 5/20 | 0.63 |
| ▸ | CA6 | P23280 | 5/20 | 0.63 |
| ▸ | CA7 | P43166 | 5/20 | 0.63 |
| ▸ | CA9 | Q16790 | 5/20 | 0.63 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.63 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.63 |
| ▸ | CA2 | P00918 | 4/20 | 0.63 |
| ▸ | CA4 | P22748 | 4/20 | 0.63 |
| ▸ | CA5A | P35218 | 4/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.63 |
| ▸ | CASP2 | P42575 | 2/20 | 0.63 |
| ▸ | F13A1 | P00488 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | THPO | P40225 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | RECQL | P46063 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Wr-1065 SCHEMBL38865 | 0.97 | — | — | |
| Wr-1065 SCHEMBL21750087 | 0.94 | ESR1 (0.94) | ESR1CA12CA6CA7CA9 | |
| SCHEMBL28279929 | 0.92 | ESR1 (0.90) | ESR1CA12CA6CA7CA9 | |
| SCHEMBL26150367 | 0.89 | — | — | |
| SCHEMBL17119217 | 0.86 | ESR1 (0.79) | ESR1CA12CA6CA7CA9 | |
| SCHEMBL7513011 | 0.86 | — | — | |
| SCHEMBL7757906 | 0.85 | — | — | |
| Wr-1065 SCHEMBL1821959 | 0.84 | ESR1 (0.74) | ESR1CA12CA6CA7CA9 | |
| SCHEMBL11228775 | 0.82 | ESR1 (0.74) | ESR1CA12CA6CA7CA9 | |
| SCHEMBL7524242 | 0.82 | ESR1 (0.74) | ESR1CA12CA6CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1437139-B1 | Method for protection against genotoxic mutagenesis | ARCH DEV CORP (US) | 2008-07-16 | — | — | EP | disclosed |
| EP-1437139-A2 | Method for protection against genotoxic mutagenesis | ARCH DEVELOPMENT CORPORATION (US) | 2004-07-14 | — | — | EP | disclosed |
| US-5891856-A | Method for protection against genotoxic mutagenesis | ARCH DEVELOPMENT CORPORATION (US) | 1999-04-06 | — | — | US | disclosed |
| US-5869338-A | Method for protection against genotoxic mutagenesis | ARCH DEVELOPMENT CORPORATION (US) | 1999-02-09 | — | — | US | disclosed |
| EP-0764027-A4 | METHOD FOR PROTECTION AGAINST GENOTOXIC MUTAGENESIS | ARCH DEV CORP (US) | 1998-04-22 | — | — | EP | disclosed |
| EP-0764027-A1 | METHOD FOR PROTECTION AGAINST GENOTOXIC MUTAGENESIS | ARCH DEVELOPMENT CORPORATION (US) | 1997-03-26 | — | — | EP | disclosed |
| US-5567686-A | Method for protection against genotoxic mutagenesis | ARCH DEVELOPMENT CORPORATION (US) | 1996-10-22 | — | — | US | disclosed |
| WO-1995007700-A1 | METHOD FOR PROTECTION AGAINST GENOTOXIC MUTAGENESIS | ARCH DEVELOPMENT CORPORATION (US) | 1995-03-23 | — | — | WO | disclosed |