SCHEMBL4640396

SCHEMBL4640396

C=CC(=O)OCCOC(=O)c1ccc(O)c(Cl)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.43
KDM4E B2RXH2 1/20 0.43
POLB P06746 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
SERPINE1 P05121 3/20 0.42
HSP90AA1 P07900 1/20 0.42
HSP90AB1 P08238 1/20 0.42
TSHR P16473 4/20 0.42
ALDH1A1 P00352 3/20 0.42
TP53 P04637 2/20 0.42
HIF1A Q16665 2/20 0.42
HSD17B10 Q99714 1/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
ESR1 P03372 3/20 0.42
PTPN1 P18031 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4639808 0.94 HDAC6 (0.47) THRBKDM4EPOLBHDAC6SERPINE1
SCHEMBL4640773 0.94 HDAC6 (0.50) KDM4EPOLBHDAC6SERPINE1HSP90AA1
SCHEMBL4640592 0.93 HDAC6 (0.52) KDM4EPOLBHDAC6SERPINE1HSP90AA1
SCHEMBL4642799 0.93 HDAC6 (0.52) KDM4EPOLBHDAC6SERPINE1HSP90AA1
SCHEMBL4642861 0.93 HDAC6 (0.52) KDM4EPOLBHDAC6SERPINE1HSP90AA1
SCHEMBL12990854 0.87 CA12 (0.57) THRBKDM4EPOLBHDAC6SERPINE1
SCHEMBL31574126 0.87 CA12 (0.57) THRBKDM4EPOLBHDAC6SERPINE1
Ethane SCHEMBL10824994 0.85 CA12 (0.53) KDM4EPOLBHDAC6SERPINE1HSP90AA1
SCHEMBL13567310 0.84 GAA (0.43) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL12394989 0.83 ALDH1A1 (0.54) THRBKDM4EPOLBHDAC6SERPINE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0461651-B1 Recording medium FUJI PHOTO FILM CO LTD (JP) 1994-02-16 EP claimed
US-5202304-A RECORDING MEDIUM FUJI PHOTO FILM CO., LTD. (JP) 1993-04-13 US claimed
EP-0461651-A1 Recording medium FUJI PHOTO FILM CO., LTD. (JP) 1991-12-18 EP claimed
EP-2135739-A2 Relief printing plate precursor for laser engraving, relief printing plate, and process for producing relief printing plate FUJIFILM Corporation (JP) 2009-12-23 EP disclosed
EP-1298490-B1 Photopolymerizable composition and recording material FUJIFILM CORP (JP) 2008-08-13 EP disclosed
US-7232644-B2 Polymerizable composition and negative-working planographic printing plate precursor using the same FUJIFILM CORPORATION (JP) 2007-06-19 US disclosed
US-7232644-B2 Polymerizable composition and negative-working planographic printing plate precursor using the same FUJIFILM CORPORATION (JP) 2007-06-19 US disclosed
US-7220529-B2 Photopolymerizable composition and recording material using the same FUJIFILM CORPORATION (JP) 2007-05-22 US disclosed
US-20070048666-A1 Two-photon recording method, two-photon absorption recording material, two-photon absorption recording-reproduction method and optical recoding medium FUJI PHOTO FILM CO., LTD. 2007-03-01 US disclosed
US-20070047038-A1 Hologram recording method, hologram recording material, optical recording medium FUJI PHOTO FILM CO., LTD. 2007-03-01 US disclosed
EP-1254780-B1 Recording material FUJI PHOTO FILM CO LTD (JP) 2007-01-03 EP disclosed
US-20020142244-A1 Photopolymerizable composition and recording material FUJI PHOTO FILM CO., LTD. 2002-10-03 US disclosed
US-20020051926-A1 Cyanine-based organic dyes, photopolymerizable compositions, and recording materials FUJI PHOTO FILM CO., LTD. (JP) 2002-05-02 US disclosed
EP-0503674-B1 Light-sensitive bistrihalomethyl-s-triazine compound and photopolymerizable composition containing same FUJI PHOTO FILM CO LTD (JP) 1998-06-24 EP disclosed
US-5484682-A FREE RADICAL INITIATOR FUJI PHOTO FILM CO., LTD. (JP) 1996-01-16 US disclosed
US-5362874-A Storage stability, discoloration inhibition FUJI PHOTO FILM CO., LTD. (JP) 1994-11-08 US disclosed
EP-0461651-B1 Recording medium FUJI PHOTO FILM CO LTD (JP) 1994-02-16 EP disclosed
US-5202304-A RECORDING MEDIUM FUJI PHOTO FILM CO., LTD. (JP) 1993-04-13 US disclosed
EP-0503674-A1 Light-sensitive bistrihalomethyl-S-triazine compound and photopolymerizable composition containing same FUJI PHOTO FILM CO., LTD. (JP) 1992-09-16 EP disclosed
EP-0461651-A1 Recording medium FUJI PHOTO FILM CO., LTD. (JP) 1991-12-18 EP disclosed