Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22774940 | 0.81 | MMP1 (0.38) | CYP2D6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL7786183 | 0.80 | MMP1 (0.34) | CYP2D6ALDH1A1TDP1 | |
| SCHEMBL6666057 | 0.79 | CYP2D6 (0.37) | CYP2D6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL740506 | 0.76 | CYP2D6 (0.32) | CYP2D6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL36622 | 0.75 | CYP2D6 (0.31) | CYP2D6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL9566596 | 0.74 | TSHR (0.33) | CYP2D6TSHR | |
| SCHEMBL4455662 | 0.73 | HDAC3 (0.34) | CYP2D6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL15834913 | 0.72 | CYP2D6 (0.51) | CYP2D6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL31548529 | 0.72 | CYP2D6 (0.51) | CYP2D6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL29028208 | 0.72 | ELANE (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954748-B1 | PREPREGS AND CURED IN PLACE SOLID SURFACES PREPARED THEREFROM | ASHLAND LICENSING & IP LLC (US) | 2018-09-26 | — | — | EP | disclosed |
| US-8741978-B2 | Prepregs and cured in place solid surfaces prepared therefrom | ASHLAND LICENSING AND INTELLECTUAL PROPERTY LLC (US) | 2014-06-03 | — | — | US | disclosed |
| EP-1954748-A2 | PREPREGS AND CURED IN PLACE SOLID SURFACES PREPARED THEREFROM | Ashland Licensing and Intellectual Property LLC (US) | 2008-08-13 | — | — | EP | disclosed |
| US-20070225443-A1 | Prepregs and cured in place solid surfaces prepared therefrom | ASHLAND LICENSING AND INTELLECTUAL PROPERTY LLC (US) | 2007-09-27 | — | — | US | disclosed |
| WO-2007064688-A2 | PREPREGS AND CURED IN PLACE SOLID SURFACES PREPARED THEREFROM | ASHLAND LICENSING AND INTELLECTUAL PROPERTY LLC (US) | 2007-06-07 | — | — | WO | disclosed |