Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 5/20 | 0.41 |
| ▸ | SAT1 | P21673 | 1/20 | 0.40 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21572857 | 1.00 | — | — | |
| SCHEMBL17277917 | 0.93 | CYP2C19 (0.44) | CYP2C19MEN1GLAKMT2ACYP1A2 | |
| SCHEMBL10099919 | 0.93 | CYP2C19 (0.44) | CYP2C19MEN1GLAKMT2ACYP1A2 | |
| SCHEMBL12612802 | 0.93 | CYP2C19 (0.52) | CYP2C19MEN1GLAKMT2ACYP1A2 | |
| SCHEMBL6733235 | 0.91 | CARM1 (0.48) | CYP2C19MEN1GLAKMT2ACYP1A2 | |
| SCHEMBL13661321 | 0.89 | HRH3 (0.48) | CYP2C19MEN1GLAKMT2ACYP1A2 | |
| SCHEMBL16492067 | 0.89 | CYP2C19 (0.41) | CYP2C19MEN1GLAKMT2ACYP1A2 | |
| SCHEMBL21727231 | 0.89 | HRH3 (0.52) | CYP2C19MEN1GLAKMT2ACYP1A2 | |
| SCHEMBL9120834 | 0.89 | HRH3 (0.52) | CYP2C19MEN1GLAKMT2ACYP1A2 | |
| SCHEMBL14446714 | 0.88 | CYP2C19 (0.39) | CYP2C19MEN1GLAKMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2524934-A2 | Thermoplastic polyurethane urea with biocidal properties and methods for producing same | GT Elektrotechnische Produkte GmbH (DE) | 2012-11-21 | — | — | EP | disclosed |
| US-20090111737-A1 | Novel antibacterial agents | THERAVANCE BIOPHARMA ANTIBIOTICS IP, LLC | 2009-04-30 | — | — | US | disclosed |
| EP-0934924-B1 | NOVEL DIAMIDE COMPOUNDS AND DRUGS CONTAINING THE SAME | KOWA CO (JP) | 2008-08-13 | — | — | EP | disclosed |
| WO-2008030390-A2 | OPHTHALMIC COMPOSITIONS FOR TREATING OCULAR HYPERTENSION | MERCK & CO., INC. (US) | 2008-03-13 | — | — | WO | disclosed |
| US-20070134729-A1 | Novel antibacterial agents | THERAVANCE BIOPHARMA ANTIBIOTICS IP, LLC | 2007-06-14 | — | — | US | disclosed |
| US-6576642-B2 | Inhibitors of the production of Ig E antibodies, antiallergens | KOWA CO., LTD. (JP) | 2003-06-10 | — | — | US | disclosed |
| US-20010039279-A1 | Diamide compounds and compositions containing the same | KOWA CO., LTD. (JP) | 2001-11-08 | — | — | US | disclosed |
| US-6297283-B1 | EXCELLENT INHIBITORY EFFECT ON THE PRODUCTION OF AN IGE ANTIBODY AND ARE HENCE USEFUL AS ANTIALLERGIC AGENTS | KOWA CO., LTD. (JP) | 2001-10-02 | — | — | US | disclosed |
| EP-0934924-A1 | NOVEL DIAMIDE COMPOUNDS AND DRUGS CONTAINING THE SAME | KOWA CO. LTD. (JP) | 1999-08-11 | — | — | EP | disclosed |
| US-4291151-A | Process for preparing polycarbonate using cyclic di- or triamine catalyst | GENERAL ELECTRIC COMPANY (US) | 1981-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010039279-A1 | Diamide compounds and compositions containing the same | HRH4, HRH2, HRH1 | CYP2C19 1000/4885MEN1 3973/4885GLA 3180/4885 |
| US-20070134729-A1 | Novel antibacterial agents | ENGASE, PGLS, PEPD | CYP2C19 2854/4885MEN1 3984/4885GLA 75/4885 |
| US-20090111737-A1 | Novel antibacterial agents | ENGASE, PGLS, PEPD | CYP2C19 2854/4885MEN1 3984/4885GLA 75/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.