Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.61 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 3/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32662877 | 1.00 | EPHX1 (0.61) | EPHX1UGT2B7CYP1A2MEN1KMT2A | |
| SCHEMBL5272958 | 0.83 | EPHX1 (0.59) | EPHX1UGT2B7CYP1A2CYP2A6TDP1 | |
| SCHEMBL22446622 | 0.79 | EPHX1 (0.56) | EPHX1UGT2B7CYP1A2CYP2A6TDP1 | |
| SCHEMBL7243544 | 0.76 | EPHX1 (0.57) | EPHX1UGT2B7CYP1A2AOC3CYP2A6 | |
| SCHEMBL27133621 | 0.76 | EPHX1 (0.38) | EPHX1UGT2B7CYP1A2 | |
| SCHEMBL95522 | 0.75 | LMNA (0.42) | HIF1A | |
| SCHEMBL21751241 | 0.75 | BCL2 (0.56) | CYP1A2MEN1KMT2ACYP2D6TSHR | |
| SCHEMBL11024562 | 0.75 | EPHX1 (0.56) | EPHX1UGT2B7MEN1KMT2ATDP1 | |
| SCHEMBL4753499 | 0.74 | EPHX1 (0.64) | EPHX1UGT2B7ANPEP | |
| SCHEMBL8779782 | 0.74 | EPHX1 (0.50) | EPHX1UGT2B7CYP1A2CYP2A6TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473484-B | Compounds useful as TRPM8 modulators | 弗门尼舍公司 | 2021-06-29 | — | — | CN | disclosed |
| EP-1954732-A1 | COMPOSITIONS FOR BRIGHTNESS ENHANCING FILMS | General Electric Company (US) | 2008-08-13 | — | — | EP | disclosed |
| WO-2007001811-A1 | COMPOSITIONS FOR BRIGHTNESS ENHANCING FILMS | GENERAL ELECTRIC COMPANY (US) | 2007-01-04 | — | — | WO | disclosed |
| US-20060293463-A1 | Compositions for brightness enhancing films | GENERAL ELECTRIC COMPANY | 2006-12-28 | — | — | US | disclosed |