SCHEMBL4640667

SCHEMBL4640667

CC(=Cc1ccccc1)C(=O)OCCS

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.53
KMT2A Q03164 7/20 0.50
MEN1 O00255 6/20 0.50
SMN1; SMN2 Q16637 3/20 0.44
RAB9A P51151 3/20 0.43
ALDH1A1 P00352 2/20 0.43
NPC1 O15118 2/20 0.43
RECQL P46063 1/20 0.42
HTT P42858 1/20 0.41
TSHR P16473 1/20 0.41
STAT1 P42224 1/20 0.40
DHODH Q02127 1/20 0.40
TRPM8 Q7Z2W7 1/20 0.40
LMNA P02545 2/20 0.40
MAPT P10636 2/20 0.40
KDM4E B2RXH2 1/20 0.40
HSP90AA1 P07900 1/20 0.40
POLB P06746 1/20 0.40
S1PR4 O95977 1/20 0.40
S1PR1 P21453 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6271227 0.91 AKR1C3 (0.47) AKR1C3KMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL7180698 0.85 AKR1C3 (0.55) AKR1C3KMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL1683262 0.85 MEN1 (0.56) AKR1C3KMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL2490770 0.84 AKR1C3 (0.53) AKR1C3KMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL3978973 0.84 AKR1C3 (0.53) AKR1C3KMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL2532167 0.83 KDM4E (0.53) AKR1C3KMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL27853769 0.83 AKR1C3 (0.51) AKR1C3KMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL7545665 0.83 AKR1C3 (0.51) AKR1C3KMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL8702266 0.83 KDM4E (0.53) AKR1C3KMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL321698 0.81 MEN1 (0.74) AKR1C3KMT2AMEN1SMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103988099-A Optical film and optical display device including the same CHEIL IND INC 2014-08-13 CN disclosed
EP-1954732-A1 COMPOSITIONS FOR BRIGHTNESS ENHANCING FILMS General Electric Company (US) 2008-08-13 EP disclosed
CN-101176019-A Light management films with zirconia particles 3M INNOVATIVE PROPERTIES CO (US) 2008-05-07 CN disclosed
EP-1828319-A1 COMPOSITIONS FOR ARTICLES COMPRISING REPLICATED MICROSTRUCTURES General Electric Company (US) 2007-09-05 EP disclosed
WO-2007001811-A1 COMPOSITIONS FOR BRIGHTNESS ENHANCING FILMS GENERAL ELECTRIC COMPANY (US) 2007-01-04 WO disclosed
US-20060293463-A1 Compositions for brightness enhancing films GENERAL ELECTRIC COMPANY 2006-12-28 US disclosed
WO-2006065542-A1 COMPOSITIONS FOR ARTICLES COMPRISING REPLICATED MICROSTRUCTURES GENERAL ELECTRIC COMPANY (US) 2006-06-22 WO disclosed
US-20060128853-A1 Compositions for articles comprising replicated microstructures GENERAL ELECTRIC COMPANY (US) 2006-06-15 US disclosed
US-20060128852-A1 Compositions for articles comprising replicated microstructures GENERAL ELECTRIC COMPANY 2006-06-15 US disclosed