SCHEMBL2490770

SCHEMBL2490770

CC(=Cc1ccccc1)C(=O)OCCN

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.53
KMT2A Q03164 6/20 0.50
MEN1 O00255 5/20 0.50
SMN1; SMN2 Q16637 3/20 0.43
RAB9A P51151 3/20 0.43
ALDH1A1 P00352 2/20 0.43
NPC1 O15118 2/20 0.43
RECQL P46063 1/20 0.42
IDO1 P14902 1/20 0.42
HTT P42858 1/20 0.41
TSHR P16473 1/20 0.41
STAT1 P42224 1/20 0.40
ESR1 P03372 1/20 0.40
CYP19A1 P11511 1/20 0.40
ESR2 Q92731 1/20 0.40
DHODH Q02127 1/20 0.40
TRPM8 Q7Z2W7 1/20 0.40
LMNA P02545 2/20 0.40
MAPT P10636 2/20 0.40
KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9116031 0.87 AKR1C3 (0.56) AKR1C3KMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL7180698 0.85 AKR1C3 (0.55) AKR1C3KMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL1683262 0.85 MEN1 (0.56) AKR1C3KMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL4640667 0.84 AKR1C3 (0.53) AKR1C3KMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL3978973 0.84 AKR1C3 (0.53) AKR1C3KMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL2532167 0.83 KDM4E (0.53) AKR1C3KMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL27853769 0.83 AKR1C3 (0.51) AKR1C3KMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL7545665 0.83 AKR1C3 (0.51) AKR1C3KMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL8702266 0.83 KDM4E (0.53) AKR1C3KMT2AMEN1SMN1; SMN2RAB9A
Styrene SCHEMBL3091250 0.82 ALDH1A1 (0.40) AKR1C3KMT2AMEN1ALDH1A1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5445743-A Methacrylate polymers as antifoulants in quench water systems NALCO CHEMICAL COMPANY (US) 1995-08-29 US claimed
EP-2832791-B1 PHENOLIC RESIN MOLDING MATERIAL, FRICTION MATERIAL, AND PHENOLIC RESIN MOLDED ARTICLE GUN EI CHEMICAL IND CO LTD (JP) 2021-02-24 EP disclosed
US-10436948-B2 Optical film, process for producing optical film, polarizer, and image display device FUJIFILM CORPORATION (JP) 2019-10-08 US disclosed
EP-3521924-A1 OPTICAL SHEET, SCREEN, AND DISPLAY DEVICE Dai Nippon Printing Co., Ltd. (JP) 2019-08-07 EP disclosed
US-10240033-B2 Optical film and method for manufacturing same, polarization plate, and liquid crystal display apparatus FUJIFILM CORPORATION (JP) 2019-03-26 US disclosed
US-9505925-B2 Phenol resin molding material, friction material, and phenol resin molded product MITSUI CHEMICALS, INC. (JP) 2016-11-29 US disclosed
US-9261732-B2 Acryl-base polymer film, optical compensation film, and liquid-crystal display device having the same FUJIFILM CORPORATION (JP) 2016-02-16 US disclosed
US-20160033687-A1 OPTICAL FILM, PROCESS FOR PRODUCING OPTICAL FILM, POLARIZER, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-02-04 US disclosed
US-20150183977-A1 OPTICAL FILM AND METHOD FOR MANUFACTURING SAME, POLARIZATION PLATE, AND LIQUID CRYSTAL DISPLAY APPARATUS FUJIFILM CORPORATION (JP) 2015-07-02 US disclosed
US-20150132656-A1 SLURRY COMPOSITION, ELECTRODE, ELECTRODE FOR NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY, AND METHOD OF MANUFACTURING ELECTRODE FOR NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY TAIYO INK MFG. CO., LTD. (JP) 2015-05-14 US disclosed
US-20100317801-A1 POLYLACTIC ACID RESIN COMPOSITION CANON KABUSHIKI KAISHA (JP) 2010-12-16 US disclosed
EP-2247666-A1 POLYLACTIC ACID RESIN COMPOSITION Canon Kabushiki Kaisha (JP) 2010-11-10 EP disclosed
US-20100245725-A1 ACRYL-BASE POLYMER FILM, OPTICAL COMPENSATION FILM, AND LIQUID-CRYSTAL DISPLAY DEVICE HAVING THE SAME FUJIFILM CORPORATION (JP) 2010-09-30 US disclosed
US-7799412-B2 Polylactic acid-based resin laminate sheet and molded product therefrom TORAY INDUSTRIES, INC. (JP) 2010-09-21 US disclosed
WO-2009131079-A1 POLYLACTIC ACID RESIN COMPOSITION CANON KABUSHIKI KAISHA (JP) 2009-10-29 WO disclosed
EP-1942001-B1 POLYLACTIC ACID RESIN MULTILAYER SHEET AND MOLDED BODY MADE OF SAME TORAY INDUSTRIES (JP) 2009-09-30 EP disclosed
US-20090169844-A1 POLYLACTIC ACID-BASED RESIN LAMINATE SHEET AND MOLDED PRODUCT THEREFROM TORAY INDUSTRIES, INC., A CORPORATION OF JAPAN (JP) 2009-07-02 US disclosed
EP-1942001-A1 POLYLACTIC ACID RESIN MULTILAYER SHEET AND MOLDED BODY MADE OF SAME TORAY INDUSTRIES, INC. (JP) 2008-07-09 EP disclosed
US-5445743-A Methacrylate polymers as antifoulants in quench water systems NALCO CHEMICAL COMPANY (US) 1995-08-29 US disclosed
US-5445743-A Methacrylate polymers as antifoulants in quench water systems NALCO CHEMICAL COMPANY (US) 1995-08-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100245725-A1 ACRYL-BASE POLYMER FILM, OPTICAL COMPENSATION FILM, AND LIQUID-CRYSTAL DISPLAY DEVICE HAVING THE SAME CFH, RPP30, BLM AKR1C3 4310/4885KMT2A 3302/4885MEN1 3439/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.