SCHEMBL4640797

SCHEMBL4640797

Cc1ccnc2c(N)cccc12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSMD14 O00487 2/20 0.61
COPS5 Q92905 2/20 0.61
CCR1 P32246 3/20 0.59
CCR8 P51685 3/20 0.59
CCR5 P51681 2/20 0.59
KDM4E B2RXH2 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
L3MBTL1 Q9Y468 3/20 0.50
HTT P42858 2/20 0.47
NR4A2 P43354 1/20 0.47
SLC6A2 P23975 1/20 0.47
ALDH1A1 P00352 2/20 0.46
MEN1 O00255 1/20 0.46
APAF1 O14727 1/20 0.46
TDP2 O95551 1/20 0.46
MAPT P10636 1/20 0.46
CASP3 P42574 1/20 0.46
KMT2A Q03164 1/20 0.46
SENP8 Q96LD8 1/20 0.46
SENP7 Q9BQF6 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinoline SCHEMBL28187658 0.84 CCR1 (0.53) PSMD14COPS5CCR1CCR8CCR5
SCHEMBL11973402 0.84 PSMD14 (0.61) PSMD14COPS5CCR1CCR8CCR5
SCHEMBL29800867 0.84 PSMD14 (0.61) PSMD14COPS5CCR1CCR8CCR5
SCHEMBL2607397 0.81 PSMD14 (0.68) PSMD14COPS5CCR1CCR8CCR5
SCHEMBL30668493 0.81 NR4A2 (0.68) KDM4ETDP1NR4A2ALDH1A1MEN1
SCHEMBL6629560 0.81 NR4A2 (0.68) KDM4ETDP1NR4A2ALDH1A1MEN1
SCHEMBL9446967 0.80 CCR1 (0.50) PSMD14COPS5CCR1CCR8CCR5
SCHEMBL13484093 0.78 CCR1 (0.68) PSMD14COPS5CCR1CCR8CCR5
SCHEMBL26523568 0.77 PSMD14 (0.58) PSMD14COPS5CCR1CCR8CCR5
SCHEMBL3271557 0.76 PSMD14 (0.61) PSMD14COPS5CCR1CCR8CCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105348281-A Synthetic method of 2, 9-dinitro-4, 7-dimethyl-1, 10-phenanthroline DING YUQIN 2016-02-24 CN claimed
CN-105348281-A Synthetic method of 2, 9-dinitro-4, 7-dimethyl-1, 10-phenanthroline DING YUQIN 2016-02-24 CN disclosed
CN-105348281-A Synthetic method of 2, 9-dinitro-4, 7-dimethyl-1, 10-phenanthroline DING YUQIN 2016-02-24 CN disclosed
US-20080124732-A1 METHOD FOR OPTICAL MEASUREMENT OF MULTI-STRANDED NUCLEIC ACID FUJIFILM CORPORATION 2008-05-29 US disclosed
EP-1889880-A2 Method for optical measurement of multi-stranded nucleic acid FUJIFILM Corporation (JP) 2008-02-20 EP disclosed
EP-1362894-B1 Method for optical measurement of multi-stranded nucleic acid using cyanine dyes FUJIFILM CORP (JP) 2007-12-19 EP disclosed
US-20050112770-A1 Method for optical measurement of multi-stranded nucleic acid FUJI PHOTO FILM CO., LTD. 2005-05-26 US disclosed
EP-0876345-B1 HETEROCYCLIC COMPOUNDS AS H+-ATPASES FUJISAWA PHARMACEUTICAL CO (JP) 2004-08-18 EP disclosed
EP-1362894-A2 Method for optical measurement of multi-stranded nucleic acid using cyanine dyes FUJI PHOTO FILM CO., LTD. (JP) 2003-11-19 EP disclosed
US-6008230-A TREATING BONE DISEASES CAUSED BY ABNORMAL BONE METABOLISM IN HUMAN BEING OR ANIMALS AS THE INHIBITORS OF BONE RESORPTION OR THE INHIBITORS OF BONE METASTASIS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1999-12-28 US disclosed
EP-0876345-A1 HETEROCYCLIC COMPOUNDS AS H+-ATPASES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1998-11-11 EP disclosed
WO-1997014681-A1 HETEROCYCLIC COMPOUNDS AS H+-ATPASES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-04-24 WO disclosed
US-4659708-A Anti-leishmanial lepidine derivatives THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1987-04-21 US disclosed