Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24963 | 0.95 | TSHR (0.52) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL1898441 | 0.93 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL4593744 | 0.93 | THRB (0.52) | TSHRTHRBPOLBAPEX1HTT | |
| 1,6-Hexanediol SCHEMBL14343519 | 0.92 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL10603114 | 0.92 | TSHR (0.60) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL3503120 | 0.92 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL870590 | 0.92 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL31636152 | 0.92 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL31636159 | 0.92 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL31636173 | 0.92 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966847-A | Contact lens from hydrophilic gel polymers of polyvinylpyrrolidone and hydroxyalkyl methacrylate | SEIDERMAN MAURICE | 1976-06-29 | — | — | US | claimed |
| EP-1302515-B1 | Coating composition based on a bimodal emulsion copolymer, methods of blocking stains, improving hiding, improving block resistance and improving shear stability | ROHM & HAAS (US) | 2008-08-06 | — | — | EP | disclosed |
| US-6818697-B2 | AQUEOUS SOLUTIONS; ANTISOILANT | ROHM AND HAAS COMPANY | 2004-11-16 | — | — | US | disclosed |
| US-20030073778-A1 | Coating composition | ROHM AND HAAS COMPANY | 2003-04-17 | — | — | US | disclosed |
| EP-1302515-A2 | Coating composition based on a bimodal emulsion copolymer, methods of blocking stains, improving hiding, improving block resistance and improving shear stability | ROHM AND HAAS COMPANY (US) | 2003-04-16 | — | — | EP | disclosed |
| EP-0052776-B1 | TWO-COAT METALLIC LACQUERING AND PROCESS FOR PREPARING IT | BASF Lacke + Farben AG (DE) | 1984-12-12 | — | — | EP | disclosed |