Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 2/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4157022 | 0.86 | SMN1; SMN2 (0.42) | KDM4ESMN1; SMN2ALDH1A1MAPTHTT | |
| SCHEMBL4159996 | 0.84 | PDGFRB (0.51) | PDGFRBPDGFRABACE1KDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL25214964 | 0.83 | PDGFRB (0.50) | PDGFRBPDGFRABACE1KDM4ESMN1; SMN2 | |
| SCHEMBL845999 | 0.71 | BACE1 (0.50) | PDGFRBPDGFRABACE1KDM4ESMN1; SMN2 | |
| SCHEMBL1073946 | 0.70 | CCR1 (0.52) | KDM4ESMN1; SMN2ALDH1A1MAPTHTT | |
| SCHEMBL31058344 | 0.70 | CCR1 (0.52) | KDM4ESMN1; SMN2ALDH1A1MAPTHTT | |
| SCHEMBL7082437 | 0.70 | ABCG2 (0.37) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL31378821 | 0.69 | ALDH1A1 (0.37) | BACE1KDM4ESMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL30241100 | 0.69 | CYP17A1 (0.34) | KDM4ENPC1L3MBTL1CASP3SENP8 | |
| SCHEMBL14678 | 0.69 | CYP1A2 (0.57) | PDGFRBPDGFRAKDM4ESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1943234-A1 | TRIAZOLE COMPOUNDS AS LIPOXYGENASE INHIBITORS | Biolipox AB (SE) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007051982-A1 | TRIAZOLE COMPOUNDS AS LIPOXYGENASE INHIBITORS | BIOLIPOX AB (SE) | 2007-05-10 | — | — | WO | disclosed |