Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 8/20 | 0.72 |
| ▸ | EGFR | P00533 | 1/20 | 0.72 |
| ▸ | KDM5A | P29375 | 1/20 | 0.55 |
| ▸ | ATP1A1 | P05023 | 2/20 | 0.53 |
| ▸ | ATP1B1 | P05026 | 2/20 | 0.53 |
| ▸ | ATP1A3 | P13637 | 2/20 | 0.53 |
| ▸ | ATP1B2 | P14415 | 2/20 | 0.53 |
| ▸ | ATP1A2 | P50993 | 2/20 | 0.53 |
| ▸ | ATP1B3 | P54709 | 2/20 | 0.53 |
| ▸ | FXYD2 | P54710 | 2/20 | 0.53 |
| ▸ | ATP1A4 | Q13733 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20754190 | 0.84 | MAOA (0.59) | MAOAEGFRKDM5AATP1A1ATP1B1 | |
| SCHEMBL30738503 | 0.84 | MAOA (1.00) | MAOAEGFRKDM5AATP1A1ATP1B1 | |
| SCHEMBL19770521 | 0.84 | MAOA (0.54) | MAOAEGFRKDM5AATP1A1ATP1B1 | |
| SCHEMBL24343638 | 0.84 | MAOA (0.59) | MAOAEGFRKDM5AATP1A1ATP1B1 | |
| SCHEMBL15527312 | 0.84 | MAOA (1.00) | MAOAEGFRKDM5AATP1A1ATP1B1 | |
| SCHEMBL25056598 | 0.84 | MAOA (0.54) | MAOAEGFRKDM5AATP1A1ATP1B1 | |
| SCHEMBL21331549 | 0.84 | AHR (0.59) | MAOAEGFRKDM5AATP1A1ATP1B1 | |
| SCHEMBL1301738 | 0.83 | MAOA (0.72) | MAOAEGFRKDM5AATP1A1ATP1B1 | |
| SCHEMBL22541881 | 0.81 | MAOA (0.51) | MAOAEGFRKDM5AMAPTHPGD | |
| SCHEMBL30241374 | 0.80 | MAOA (0.71) | MAOAEGFRKDM5AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1885709-A2 | BENZOFURAN DERIVATIVES WITH THERAPEUTIC ACTIVITIES | Pharmos Corporation (US) | 2008-02-13 | — | — | EP | claimed |
| WO-2006129318-A2 | BENZOFURAN DERIVATIVES WITH THERAPEUTIC ACTIVITIES | PHARMOS CORPORATION (US) | 2006-12-07 | — | — | WO | claimed |