Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4459210 | 0.77 | MEN1 (0.48) | TSHRALDH1A1MAPK1 | |
| SCHEMBL176168 | 0.77 | MEN1 (0.48) | TSHRALDH1A1MAPK1 | |
| SCHEMBL14269358 | 0.77 | MEN1 (0.48) | TSHRALDH1A1MAPK1 | |
| SCHEMBL46409 | 0.77 | TSHR (0.32) | TSHRMAPK1 | |
| SCHEMBL541813 | 0.75 | TSHR (0.39) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL4976681 | 0.75 | TSHR (0.60) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL8198631 | 0.75 | TSHR (0.60) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL8191937 | 0.75 | TSHR (0.60) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL29212545 | 0.75 | TSHR (0.60) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL4608703 | 0.75 | TSHR (0.60) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011140644-A1 | POLYACETAL OR POLYKETAL AND ETHER POLYMERS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2011-11-17 | — | — | WO | disclosed |