SCHEMBL4641827

SCHEMBL4641827

CC(=O)OC(=O)Cc1ccc(Cl)cc1

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.54
KMT2A Q03164 1/20 0.53
MAPT P10636 3/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
TSHR P16473 2/20 0.50
ALDH1A1 P00352 2/20 0.49
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
KLK7 P49862 1/20 0.46
CTBP2 P56545 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8855417 0.88 POLB (0.56) POLBKMT2AMAPTL3MBTL1TSHR
SCHEMBL13360707 0.85 POLB (0.51) POLBKMT2AMAPTL3MBTL1TSHR
SCHEMBL4659000 0.82 CA2 (0.52) KMT2AL3MBTL1ALDH1A1NPC1RAB9A
SCHEMBL3369104 0.82 KMT2A (0.46) KMT2AMAPTL3MBTL1NPC1RAB9A
SCHEMBL7896900 0.81 CYP4F2 (0.42) POLBKMT2AL3MBTL1TSHRALDH1A1
SCHEMBL4641821 0.81 POLB (0.50) POLBKMT2AMAPTL3MBTL1TSHR
SCHEMBL4642293 0.81 KMT2A (0.49) POLBKMT2AALDH1A1KLK7CTBP2
SCHEMBL4647098 0.80 POLB (0.50) POLBKMT2AMAPTL3MBTL1TSHR
SCHEMBL248114 0.80 TSHR (0.58) KMT2AL3MBTL1TSHRALDH1A1
SCHEMBL191324 0.80 CYP4F2 (0.63) POLBKMT2AMAPTL3MBTL1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed
US-5691333-A APPLYING TO CONTROL ARTHROPODS AND NEMATODES RHONE-POULENC INC. (US) 1997-11-25 US disclosed
US-5629335-A Pesticidal 1-arylpyrazole-3-carboximidothioic acid esters RHONE-POULENC INC. (US) 1997-05-13 US disclosed
US-4349556-A Pesticidally active 1-acyloxy-1-phenyl-2-azolyl-ethanes BAYER AKTIENGESELLSCHAFT (DE) 1982-09-14 US disclosed