SCHEMBL4642108

SCHEMBL4642108

C=CC(=O)OC(C)Sc1ccc2ccccc2c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.52
MAPT P10636 3/20 0.43
ALDH1A1 P00352 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
KDM4E B2RXH2 1/20 0.43
EGFR P00533 1/20 0.43
TP53 P04637 1/20 0.43
CYP3A4 P08684 1/20 0.43
PKM P14618 1/20 0.43
HPGD P15428 1/20 0.43
ALOX15 P16050 1/20 0.43
ALOX12 P18054 1/20 0.43
JAK1 P23458 1/20 0.43
MAPK1 P28482 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
ANPEP P15144 1/20 0.39
RXFP1 Q9HBX9 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL42561 0.83 LMNA (0.38) ALDH1A1SMN1; SMN2KDM4EPKMMAPK1
SCHEMBL8028282 0.82 EPHX1 (0.46) EPHX1MAPTALDH1A1MEN1KMT2A
SCHEMBL16709775 0.79 HCAR2 (0.43) EPHX1MAPTALDH1A1MEN1KMT2A
SCHEMBL10455357 0.78 HPGD (0.34) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL7524590 0.78 HPGD (0.49) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL1218505 0.77 MAPT (0.45) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL5267799 0.77 UGT2B7 (0.49) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL23722516 0.76 ANPEP (0.44) EPHX1MAPTALDH1A1MEN1KMT2A
SCHEMBL4350006 0.76 HDAC3 (0.37) ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E
SCHEMBL16709702 0.76 EPHX1 (0.39) EPHX1MAPTALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9368736-B2 Flexible display apparatus SAMSUNG DISPLAY CO, LTD. (KR) 2016-06-14 US claimed
US-20150115229-A1 FLEXIBLE DISPLAY APPARATUS SAMSUNG DISPLAY CO., LTD. (KR) 2015-04-30 US claimed
WO-2000079312-A1 HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS BAUSCH & LOMB SURGICAL, INC. (US) 2000-12-28 WO claimed
US-11505653-B2 Compositions and methods of making a polymerized composition 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-11-22 US disclosed
CN-115167075-A Photopolymer and grating initiated by disperse dye macromolecules and preparation method thereof 杭州光粒科技有限公司 2022-10-11 CN disclosed
CN-111372959-B Photopolymerizable compositions, articles, and methods comprising a urethane component and a monofunctional reactive diluent 3M创新有限公司 2022-09-02 CN disclosed
CN-114585604-A Dicarboxylic acid compound, inorganic particle treated with dicarboxylic acid compound, and composition thereof 3M创新有限公司 2022-06-03 CN disclosed
CN-112759959-B Photopolymer composition and optical grating 杭州光粒科技有限公司 2022-04-29 CN disclosed
CN-113840886-A Composition comprising styrene-isoprene block copolymer and ethylenically unsaturated monomer 3M创新有限公司 2021-12-24 CN disclosed
CN-113286560-A Orthodontic articles and methods of making and post-treating the same 3M创新有限公司 2021-08-20 CN disclosed
CN-112764159-A Optical waveguide element, method for producing the same, and holographic optical waveguide display device 杭州光粒科技有限公司 2021-05-07 CN disclosed
CN-111615377-A Orthodontic articles comprising cured free-radically polymerizable compositions containing polymers or macromolecules with photoinitiating groups 3M创新有限公司 2020-09-01 CN disclosed
CN-111372959-A Photopolymerizable compositions, articles, and methods comprising a urethane component and a monofunctional reactive diluent 3M创新有限公司 2020-07-03 CN disclosed
CN-110945054-A Compositions and methods for preparing polymeric compositions 3M创新有限公司 2020-03-31 CN disclosed
US-9368736-B2 Flexible display apparatus SAMSUNG DISPLAY CO, LTD. (KR) 2016-06-14 US disclosed
US-20150115229-A1 FLEXIBLE DISPLAY APPARATUS SAMSUNG DISPLAY CO., LTD. (KR) 2015-04-30 US disclosed
EP-1954732-A1 COMPOSITIONS FOR BRIGHTNESS ENHANCING FILMS General Electric Company (US) 2008-08-13 EP disclosed
WO-2007001811-A1 COMPOSITIONS FOR BRIGHTNESS ENHANCING FILMS GENERAL ELECTRIC COMPANY (US) 2007-01-04 WO disclosed
US-20060293463-A1 Compositions for brightness enhancing films GENERAL ELECTRIC COMPANY 2006-12-28 US disclosed
WO-2000079312-A1 HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS BAUSCH & LOMB SURGICAL, INC. (US) 2000-12-28 WO disclosed