SCHEMBL4642207

SCHEMBL4642207

CCC[CH]C(=O)O[Si](CCCC)(CCCC)CCCC

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.35
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33
FAAH O00519 3/20 0.32
SOAT1 P35610 2/20 0.32
MEN1 O00255 1/20 0.32
TP53 P04637 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C19 P33261 1/20 0.32
KMT2A Q03164 1/20 0.32
HCAR2 Q8TDS4 3/20 0.32
MAPT P10636 1/20 0.31
RAB9A P51151 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
CNR1 P21554 1/20 0.31
KDM4E B2RXH2 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4642510 0.94 FAAH (0.35) ATMHPGDTSHRFAAHSOAT1
SCHEMBL4641766 0.93 FAAH (0.38) FAAHSOAT1MEN1TP53CYP1A2
SCHEMBL4645312 0.93 FAAH (0.38) FAAHSOAT1MEN1TP53CYP1A2
SCHEMBL4642477 0.88
SCHEMBL4643727 0.86 ATM (0.36) ATMHPGDTSHRHCAR2MAPT
SCHEMBL4645335 0.83 ATM (0.34) ATMHPGDTSHRHCAR2
SCHEMBL5973432 0.82 ATM (0.48) ATMHPGDTSHRHCAR2MAPT
SCHEMBL5973441 0.82 ATM (0.48) ATMHPGDTSHRHCAR2MAPT
SCHEMBL4642054 0.82 ATM (0.30) ATM
SCHEMBL5973762 0.82 ATM (0.48) ATMHPGDTSHRHCAR2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed