SCHEMBL4642271

SCHEMBL4642271

O=Cc1cc(OC(F)(F)F)ccc1OC(=O)CCCCCl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.43
FFAR4 Q5NUL3 9/20 0.39
FFAR1 O14842 5/20 0.39
SCN5A Q14524 2/20 0.39
CYP2C9 P11712 1/20 0.39
MRGPRX4 Q96LA9 1/20 0.37
RAB9A P51151 2/20 0.37
KDM4E B2RXH2 1/20 0.37
PPARD Q03181 1/20 0.36
PPARA Q07869 1/20 0.36
CYP3A4 P08684 1/20 0.36
KCNH2 Q12809 1/20 0.36
CACNA1C Q13936 1/20 0.36
HDAC3 O15379 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC7 Q8WUI4 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC10 Q969S8 1/20 0.35
HDAC11 Q96DB2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4647390 0.96 KMT2A (0.40) KMT2AFFAR4FFAR1SCN5ACYP2C9
SCHEMBL4645690 0.91 TOP2A (0.39) KMT2AFFAR4FFAR1SCN5ACYP2C9
SCHEMBL4642032 0.90 KMT2A (0.43) KMT2AFFAR4FFAR1SCN5ACYP2C9
SCHEMBL4644696 0.89 KMT2A (0.40) KMT2AFFAR4FFAR1SCN5ACYP2C9
SCHEMBL4645139 0.88 KMT2A (0.43) KMT2AFFAR4FFAR1SCN5ACYP2C9
SCHEMBL4642511 0.87 MRGPRX4 (0.37) KMT2AFFAR4FFAR1SCN5ACYP2C9
SCHEMBL4641889 0.86 FFAR1 (0.37) KMT2AFFAR4FFAR1SCN5ACYP2C9
SCHEMBL4641857 0.85 KDM4E (0.51) KMT2ARAB9AKDM4ENPC1LMNA
SCHEMBL4645692 0.85 KDM4E (0.36) KMT2AFFAR4FFAR1SCN5ACYP2C9
SCHEMBL4641911 0.83 KDM4E (0.38) KMT2AFFAR4FFAR1SCN5ACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed