SCHEMBL4645692

SCHEMBL4645692

[CH2]CCC(=O)Oc1ccc(OC(F)(F)F)cc1C=O

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.36
RAB9A P51151 1/20 0.36
KMT2A Q03164 2/20 0.35
POLB P06746 1/20 0.35
FFAR1 O14842 5/20 0.34
FFAR4 Q5NUL3 5/20 0.34
MRGPRX4 Q96LA9 3/20 0.34
BACE1 P56817 1/20 0.34
SLC6A2 P23975 2/20 0.33
SLC6A4 P31645 2/20 0.33
GAA P10253 1/20 0.33
EPHX2 P34913 1/20 0.33
CYP2C9 P11712 1/20 0.33
SCN5A Q14524 1/20 0.33
PIM1 P11309 1/20 0.33
CETP P11597 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4645139 0.93 KMT2A (0.43) KDM4ERAB9AKMT2APOLBFFAR1
SCHEMBL4645031 0.90 KDM4E (0.37) KDM4ERAB9AKMT2APOLBMRGPRX4
SCHEMBL4645690 0.88 TOP2A (0.39) KDM4ERAB9AKMT2APOLBFFAR1
SCHEMBL4641889 0.88 FFAR1 (0.37) KDM4ERAB9AKMT2APOLBFFAR1
SCHEMBL4647390 0.86 KMT2A (0.40) KDM4ERAB9AKMT2APOLBFFAR1
SCHEMBL4644696 0.86 KMT2A (0.40) KDM4ERAB9AKMT2APOLBFFAR1
SCHEMBL4641911 0.85 KDM4E (0.38) KDM4ERAB9AKMT2APOLBFFAR1
SCHEMBL4642271 0.85 KMT2A (0.43) KDM4ERAB9AKMT2AFFAR1FFAR4
SCHEMBL4642032 0.85 KMT2A (0.43) KDM4ERAB9AKMT2APOLBFFAR1
SCHEMBL4642511 0.84 MRGPRX4 (0.37) KDM4ERAB9AKMT2APOLBFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed