SCHEMBL4642285

SCHEMBL4642285

[CH2]C(=O)OC(=O)Cc1ccc(F)cc1

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.49
GAA P10253 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.45
CTBP2 P56545 1/20 0.44
KLK7 P49862 4/20 0.43
ALDH1A1 P00352 2/20 0.43
MEN1 O00255 1/20 0.42
TDP1 Q9NUW8 2/20 0.42
POLB P06746 1/20 0.42
APEX1 P27695 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
RAB9A P51151 1/20 0.41
EGFR P00533 1/20 0.41
ERBB2 P04626 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4642443 0.83 KMT2A (0.47) KMT2AGAASMN1; SMN2CTBP2KLK7
SCHEMBL4642293 0.81 KMT2A (0.49) KMT2AGAASMN1; SMN2CTBP2KLK7
SCHEMBL4641821 0.81 POLB (0.50) KMT2ACTBP2KLK7ALDH1A1TDP1
SCHEMBL4647338 0.80 KMT2A (0.45) KMT2AGAASMN1; SMN2CTBP2KLK7
SCHEMBL4642266 0.80 ALDH1A1 (0.57) KMT2ASMN1; SMN2CTBP2ALDH1A1MEN1
SCHEMBL4644036 0.78 KMT2A (0.56) KMT2AGAASMN1; SMN2CTBP2KLK7
SCHEMBL27845956 0.78 KMT2A (0.53) KMT2AGAASMN1; SMN2CTBP2KLK7
SCHEMBL4642742 0.78 KMT2A (0.47) KMT2AGAASMN1; SMN2CTBP2KLK7
SCHEMBL2798507 0.77 GAA (0.53) KMT2AGAASMN1; SMN2CTBP2ALDH1A1
SCHEMBL4642440 0.77 KMT2A (0.49) KMT2AGAASMN1; SMN2CTBP2KLK7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed