SCHEMBL4642399

SCHEMBL4642399

COC(=O)C=CC(=O)OCC(=O)OC(=O)Cc1ccc(OC)cc1

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KLK7 P49862 5/20 0.51
HTT P42858 1/20 0.48
POLB P06746 1/20 0.46
ALDH1A1 P00352 2/20 0.46
KMT2A Q03164 1/20 0.46
GAA P10253 1/20 0.46
MAPT P10636 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2C19 P33261 1/20 0.45
KDM4E B2RXH2 1/20 0.45
TRPV1 Q8NER1 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4646919 1.00 KLK7 (0.51) KLK7HTTPOLBALDH1A1KMT2A
SCHEMBL4642387 1.00 KLK7 (0.51) KLK7HTTPOLBALDH1A1KMT2A
SCHEMBL4645420 0.91 KMT2A (0.50) KLK7HTTALDH1A1KMT2AGAA
SCHEMBL4644975 0.91 KMT2A (0.50) KLK7HTTALDH1A1KMT2AGAA
SCHEMBL4644966 0.91 KMT2A (0.50) KLK7HTTALDH1A1KMT2AGAA
SCHEMBL4646096 0.87 ALDH1A1 (0.47) KLK7HTTPOLBALDH1A1KMT2A
SCHEMBL4646083 0.87 ALDH1A1 (0.47) KLK7HTTPOLBALDH1A1KMT2A
SCHEMBL4647774 0.86 MAPT (0.49) KLK7POLBALDH1A1KMT2AMAPT
SCHEMBL4645084 0.86 MAPT (0.49) KLK7POLBALDH1A1KMT2AMAPT
SCHEMBL4645073 0.86 MAPT (0.49) KLK7POLBALDH1A1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed