SCHEMBL4642740

SCHEMBL4642740

NCCC(=O)OC1CCCCC1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 2/20 0.58
CYP2C19 P33261 1/20 0.50
HTT P42858 1/20 0.47
CYP19A1 P11511 2/20 0.45
EPHX1 P07099 2/20 0.44
ALDH1A1 P00352 4/20 0.43
KDM4E B2RXH2 2/20 0.43
HPGD P15428 2/20 0.43
LMNA P02545 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.41
HSD17B10 Q99714 1/20 0.38
RAB9A P51151 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
MMP9 P14780 2/20 0.37
MMP12 P39900 2/20 0.37
MMP1 P03956 1/20 0.37
FABP7 O15540 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18681694 1.00 NAAA (0.58) NAAACYP2C19HTTCYP19A1EPHX1
SCHEMBL15727148 1.00 NAAA (0.58) NAAACYP2C19HTTCYP19A1EPHX1
SCHEMBL24530568 0.89
SCHEMBL8726974 0.88 NAAA (0.64) NAAACYP2C19HTTCYP19A1EPHX1
SCHEMBL781576 0.87 NAAA (0.46) NAAACYP2C19HTTCYP19A1EPHX1
SCHEMBL31069913 0.87 NAAA (0.66) NAAACYP2C19HTTCYP19A1EPHX1
SCHEMBL258780 0.87 NAAA (0.66) NAAACYP2C19HTTCYP19A1EPHX1
SCHEMBL7568980 0.87 NAAA (0.66) NAAACYP2C19HTTCYP19A1EPHX1
Hydrochloric Acid SCHEMBL8726966 0.86 NAAA (0.62) NAAACYP2C19HTTCYP19A1EPHX1
SCHEMBL8104397 0.85 NAAA (0.70) NAAACYP2C19HTTCYP19A1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117551039-A Aryl formamide compound, preparation method thereof and application of aryl formamide compound in resisting enterovirus EV71 武汉大学 2024-02-13 CN claimed
CN-1325378-A Process for the synthesis of 1-(aminomethyl) cyclohexyl-acetic acid RICHTER GEDEON VEGY ZETI GY & (HU) 2001-12-05 CN claimed
CN-113735700-B Synthesis process of gabapentin intermediate 扬州工业职业技术学院 2023-07-28 CN disclosed
WO-2022129041-A1 PRODRUGS OF 3-BENZOAMIDO-2-AMINOPROPIONIC ACID DERIVATIVES AS MODULATORS OF THE NMDA RECEPTOR H. LUNDBECK A/S (DK) 2022-06-23 WO disclosed
CN-114645027-A Aminotransferase mutant from bacillus megatherium and application thereof 上海合全药物研发有限公司 2022-06-21 CN disclosed
CN-113735700-A Synthesis process of gabapentin intermediate 扬州工业职业技术学院 2021-12-03 CN disclosed
WO-2021001420-A1 PRODRUGS OF MODULATORS OF THE NMDA RECEPTOR H. LUNDBECK A/S (DK) 2021-01-07 WO disclosed
WO-2018141796-A1 NOVEL METHODS FOR SUB-TYPING AND TREATING CANCER HI-STEM GGMBH (DE) 2018-08-09 WO disclosed
US-9309285-B2 Macrocyclic broad spectrum antibiotics RQX PHARMACEUTICALS, INC. (US) 2016-04-12 US disclosed
CN-105440032-A PYRAZINE DERIVATIVES AS ENAC BLOCKERS NOVARTIS AG 2016-03-30 CN disclosed
CN-103249723-B Pyrazine derivatives as ENAC blockers NOVARTIS AG (CH) 2015-11-25 CN disclosed
EP-0711760-B1 METHOD OF ALKYLATING TRIAZINE DERIVATIVE NISSAN CHEMICAL IND LTD (JP) 2002-05-15 EP disclosed
WO-2000032167-A9 A POLYSOME SDG INC (US) 2001-12-13 WO disclosed
US-6130332-A USING A GROUP 8 METAL CATALYST AND ALDEHYDES OR KETONE NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2000-10-10 US disclosed
WO-2000032167-A1 A POLYSOME SDG, INC. (US) 2000-06-08 WO disclosed
EP-0969823-A2 ANTI-EPILEPTOGENIC AGENTS QUEEN'S UNIVERSITY AT KINGSTON (CA) 2000-01-12 EP disclosed
WO-1998040055-A2 ANTI-EPILEPTOGENIC AGENTS QUEEN'S UNIVERSITY AT KINGSTON (CA) 1998-09-17 WO disclosed
US-5792867-A Method of alkylating of triazine derivatives NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1998-08-11 US disclosed
EP-0760369-A1 PROCESS FOR ALKYLATING TRIAZINE DERIVATIVE NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1997-03-05 EP disclosed
EP-0711760-A1 METHOD OF ALKYLATING TRIAZINE DERIVATIVE NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1996-05-15 EP disclosed