SCHEMBL4642771

SCHEMBL4642771

CCC[C@H]1CC[C@H](C2CCC(C3Cc4cc(F)c(F)c(F)c4C3)CC2)CC1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FYN P06241 1/20 0.35
TLR4 O00206 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4645247 1.00 FYN (0.35) FYNTLR4
SCHEMBL4642776 1.00 FYN (0.35) FYNTLR4
SCHEMBL4642780 1.00 FYN (0.35) FYNTLR4
SCHEMBL4645255 1.00 FYN (0.35) FYNTLR4
SCHEMBL14525797 0.89 TLR4 (0.36) FYNTLR4
SCHEMBL14525735 0.89 TLR4 (0.36) FYNTLR4
SCHEMBL7619012 0.89 TLR4 (0.36) FYNTLR4
SCHEMBL9391219 0.85 FYN (0.44) FYNTLR4
SCHEMBL9391704 0.85 FYN (0.44) FYNTLR4
SCHEMBL9391697 0.85 FYN (0.44) FYNTLR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1568754-B1 NEMATIC LIQUID CRYSTAL COMPOSITION CONTAINING INDAN COMPOUND DAINIPPON INK & CHEMICALS (JP) 2008-08-13 EP disclosed
US-7232592-B2 Compounds having a 4,6-difluoroindan-2,5-diyl group; composition of up to 6 compounds gives good response speed, good electrooptical liquid crystal display, matrix liquid crystal display elements DAINIPPON INK AND CHEMICALS, INC. (JP) 2007-06-19 US disclosed
US-20060102878-A1 Nematic liquid crystal composition containing indan compound DAINIPPON INK AND CHEMICALS, INC. (JP) 2006-05-18 US disclosed
EP-1568754-A1 NEMATIC LIQUID CRYSTAL COMPOSITION CONTAINING INDAN COMPOUND DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-08-31 EP disclosed