Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 2/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14525735 | 1.00 | TLR4 (0.36) | TLR4FYNDRD2DRD3 | |
| SCHEMBL14525797 | 1.00 | TLR4 (0.36) | TLR4FYNDRD2DRD3 | |
| SCHEMBL4645255 | 0.89 | FYN (0.35) | TLR4FYN | |
| SCHEMBL4642780 | 0.89 | FYN (0.35) | TLR4FYN | |
| SCHEMBL4642776 | 0.89 | FYN (0.35) | TLR4FYN | |
| SCHEMBL4645247 | 0.89 | FYN (0.35) | TLR4FYN | |
| SCHEMBL4642771 | 0.89 | FYN (0.35) | TLR4FYN | |
| SCHEMBL14526561 | 0.88 | TLR4 (0.34) | TLR4FYN | |
| SCHEMBL14526581 | 0.88 | TLR4 (0.34) | TLR4FYN | |
| SCHEMBL18137086 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002284722-A | METHOD FOR PRODUCING 5,6,7-TRIFLUORO-1,2,3,4- TETRAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK & CHEM INC | 2002-10-03 | — | — | JP | disclosed |