Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4648198 | 0.95 | TSHR (0.40) | TLR4TSHRMAPTCYP2C9LMNA | |
| SCHEMBL6050318 | 0.78 | — | — | |
| SCHEMBL9442481 | 0.75 | TLR4 (0.37) | TLR4MAPTCYP2C9LMNAALDH1A1 | |
| SCHEMBL27773749 | 0.75 | SAT1 (0.41) | TSHRMAPTKMT2ACHRM2CHRM4 | |
| SCHEMBL10706434 | 0.75 | TLR4 (0.43) | TLR4MAPTCYP2C9LMNAALDH1A1 | |
| SCHEMBL4642806 | 0.75 | ALDH1A1 (0.44) | TLR4TSHRMAPTCYP2C9LMNA | |
| SCHEMBL8732696 | 0.75 | TLR4 (0.43) | TLR4MAPTCYP2C9LMNAALDH1A1 | |
| SCHEMBL11042732 | 0.75 | TLR4 (0.43) | TLR4MAPTCYP2C9LMNAALDH1A1 | |
| SCHEMBL4642815 | 0.75 | ALDH1A1 (0.44) | TLR4TSHRMAPTCYP2C9LMNA | |
| SCHEMBL4642812 | 0.75 | ALDH1A1 (0.44) | TLR4TSHRMAPTCYP2C9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1568754-B1 | NEMATIC LIQUID CRYSTAL COMPOSITION CONTAINING INDAN COMPOUND | DAINIPPON INK & CHEMICALS (JP) | 2008-08-13 | — | — | EP | disclosed |
| US-7232592-B2 | Compounds having a 4,6-difluoroindan-2,5-diyl group; composition of up to 6 compounds gives good response speed, good electrooptical liquid crystal display, matrix liquid crystal display elements | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2007-06-19 | — | — | US | disclosed |
| US-20060102878-A1 | Nematic liquid crystal composition containing indan compound | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2006-05-18 | — | — | US | disclosed |
| EP-1568754-A1 | NEMATIC LIQUID CRYSTAL COMPOSITION CONTAINING INDAN COMPOUND | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-08-31 | — | — | EP | disclosed |