Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4642313 | 0.90 | CYP1A2 (0.56) | ALDH1A1HTTHPGDSMN1; SMN2MEN1 | |
| SCHEMBL4642408 | 0.89 | CYP1A2 (0.50) | ALDH1A1HTTHPGDSMN1; SMN2MEN1 | |
| SCHEMBL7667574 | 0.86 | ALDH1A1 (0.50) | ALDH1A1HTTHPGDSMN1; SMN2MEN1 | |
| SCHEMBL2495602 | 0.83 | ALDH1A1 (0.52) | ALDH1A1HTTHPGDSMN1; SMN2MEN1 | |
| SCHEMBL27533288 | 0.82 | ALDH1A1 (0.50) | ALDH1A1HTTHPGDSMN1; SMN2MEN1 | |
| SCHEMBL3200496 | 0.82 | ALDH1A1 (0.50) | ALDH1A1HTTHPGDSMN1; SMN2MEN1 | |
| 1,2-Dipropoxybenzene SCHEMBL29428926 | 0.80 | CYP1A2 (0.56) | ALDH1A1HTTMEN1KMT2ACYP1A2 | |
| 1,2-Dipropoxybenzene SCHEMBL578657 | 0.80 | CYP1A2 (0.56) | ALDH1A1HTTMEN1KMT2ACYP1A2 | |
| SCHEMBL812635 | 0.80 | ALDH1A1 (0.77) | ALDH1A1HTTHPGDSMN1; SMN2MEN1 | |
| SCHEMBL2098846 | 0.80 | HPGD (0.48) | ALDH1A1HTTHPGDSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1130017-B1 | Azole derivatives and their use as superoxide radical inhibitors | OTSUKA PHARMA CO LTD (JP) | 2005-06-15 | — | — | EP | claimed |
| EP-1630606-B1 | POSITIVE PHOTOSENSITIVE COMPOSITION | THINK LABS KK (JP) | 2008-08-13 | — | — | EP | disclosed |
| US-20070212640-A1 | Positive Photosensitive Composition | THINK LABORATORY CO., LTD. (JP) | 2007-09-13 | — | — | US | disclosed |
| EP-1775632-A1 | POSITIVE-WORKING PHOTOSENSITIVE COMPOSITION | THINK LABORATORY CO., LTD. (JP) | 2007-04-18 | — | — | EP | disclosed |
| US-20060222998-A1 | Positive photosensitive composition | THINK LABORATORY CO., LTD. (JP) | 2006-10-05 | — | — | US | disclosed |
| EP-1630606-A1 | POSITIVE PHOTOSENSITIVE COMPOSITION | THINK LABORATORY CO., LTD. (JP) | 2006-03-01 | — | — | EP | disclosed |
| EP-1130017-B1 | Azole derivatives and their use as superoxide radical inhibitors | OTSUKA PHARMA CO LTD (JP) | 2005-06-15 | — | — | EP | disclosed |
| EP-0934937-B1 | Azole derivatives as superoxide radical inhibitor | OTSUKA PHARMA CO LTD (JP) | 2002-02-27 | — | — | EP | disclosed |
| US-RE37556-E1 | (ALKOXYPHENYL)THIAZOLE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2002-02-19 | — | — | US | disclosed |
| EP-1130017-A2 | Azole derivatives and their use as superoxide radical inhibitors | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6080764-A | PROTECTING VARIOUS TISSUE CELLS FROM DISTURBANCES ASSOCIATED WITH ISCHEMIA AND BLOOD REPERFUSION IN HEART, BRAIN, KIDNEY, LUNG AND DIGESTIVE TRACT BY INHIBITING SUPEROXIDE-RELEASE BY NEUTROPHILIC LEUKOCYTES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2000-06-27 | — | — | US | disclosed |
| EP-0934937-A1 | Azole derivatives as superoxide radical inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-11 | — | — | EP | disclosed |
| US-5677319-A | THIAZOLE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-10-14 | — | — | US | disclosed |
| US-5643932-A | PREVENTS CELL DAMAGE AFTER ISCHEMIA AND RE-PERFUSION, SUBSTITUTED THIAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0513387-A1 | ACTIVE OXYGEN INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-19 | — | — | EP | disclosed |