SCHEMBL4643263

SCHEMBL4643263

[CH2]CC(=O)Oc1ccc(C=O)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.68
ALDH1A1 P00352 9/20 0.45
CYP2A6 P11509 1/20 0.45
PARP10 Q53GL7 1/20 0.44
PARP3 Q9Y6F1 1/20 0.44
MAPT P10636 3/20 0.44
KDM4E B2RXH2 3/20 0.44
LMNA P02545 3/20 0.41
ALDH1A3 P47895 1/20 0.41
HTT P42858 1/20 0.41
HSD17B10 Q99714 1/20 0.41
STS P08842 1/20 0.40
ALDH5A1 P51649 1/20 0.40
ABAT P80404 1/20 0.40
SMN1; SMN2 Q16637 3/20 0.39
HPGD P15428 1/20 0.39
DRD1 P21728 1/20 0.38
ESR1 P03372 1/20 0.38
RECQL P46063 1/20 0.38
HIF1A Q16665 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4646093 0.85 KMT2A (0.74) KMT2AALDH1A1CYP2A6PARP10PARP3
SCHEMBL13481050 0.84 KMT2A (0.85) KMT2AALDH1A1CYP2A6PARP10PARP3
SCHEMBL29325146 0.84 KMT2A (0.72) KMT2AALDH1A1CYP2A6PARP10PARP3
SCHEMBL4646697 0.84 KMT2A (0.83) KMT2AALDH1A1CYP2A6PARP10PARP3
SCHEMBL4642075 0.82 KMT2A (0.70) KMT2AALDH1A1CYP2A6PARP10PARP3
SCHEMBL14575315 0.81 KMT2A (0.93) KMT2AALDH1A1CYP2A6PARP10PARP3
SCHEMBL4641673 0.81 KMT2A (0.68) KMT2AALDH1A1CYP2A6PARP10PARP3
SCHEMBL14575820 0.81 KMT2A (1.00) KMT2AALDH1A1CYP2A6PARP10PARP3
SCHEMBL1564782 0.81 KMT2A (0.68) KMT2AALDH1A1CYP2A6PARP10PARP3
SCHEMBL4646026 0.79 KMT2A (0.77) KMT2AALDH1A1CYP2A6PARP10PARP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed