SCHEMBL4646697

SCHEMBL4646697

[CH2]CCCC(=O)Oc1ccc(C=O)cc1

nearest known ligand 0.83

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.83
EGFR P00533 5/20 0.47
ERBB2 P04626 5/20 0.47
ALDH1A1 P00352 4/20 0.46
MAPT P10636 3/20 0.46
LMNA P02545 2/20 0.46
HTT P42858 1/20 0.46
HSD17B10 Q99714 1/20 0.46
CYP2A6 P11509 1/20 0.41
PARP10 Q53GL7 1/20 0.41
PARP3 Q9Y6F1 1/20 0.41
KDM4E B2RXH2 1/20 0.41
PRSS1 P07477 1/20 0.41
PRSS2 P07478 1/20 0.41
PRSS3 P35030 1/20 0.41
HPGD P15428 5/20 0.40
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4646093 0.91 KMT2A (0.74) KMT2AEGFRERBB2ALDH1A1MAPT
SCHEMBL14575315 0.91 KMT2A (0.93) KMT2AEGFRERBB2ALDH1A1MAPT
SCHEMBL14575820 0.91 KMT2A (1.00) KMT2AEGFRERBB2ALDH1A1MAPT
SCHEMBL13481050 0.87 KMT2A (0.85) KMT2AEGFRERBB2ALDH1A1MAPT
SCHEMBL4643895 0.86 KMT2A (0.83) KMT2AEGFRERBB2ALDH1A1MAPT
SCHEMBL4641512 0.85 KMT2A (0.87) KMT2AEGFRERBB2ALDH1A1MAPT
SCHEMBL7285233 0.85 KMT2A (0.81) KMT2AEGFRERBB2ALDH1A1MAPT
SCHEMBL4647186 0.85 KMT2A (0.81) KMT2AEGFRERBB2ALDH1A1MAPT
SCHEMBL4643263 0.84 KMT2A (0.68) KMT2AALDH1A1MAPTLMNAHTT
SCHEMBL4642546 0.83 KMT2A (0.84) KMT2AEGFRERBB2ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed