SCHEMBL4643357

SCHEMBL4643357

[CH2]C(=O)Oc1ccc(C=O)cc1OC

nearest known ligand 0.68

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.68
TSHR P16473 1/20 0.68
KDM4E B2RXH2 1/20 0.61
MAPT P10636 1/20 0.61
FDPS P14324 1/20 0.58
AOX1 Q06278 1/20 0.57
TRIM24 O15164 1/20 0.57
HPGD P15428 1/20 0.57
ALDH5A1 P51649 1/20 0.57
ABAT P80404 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
TRIM33 Q9UPN9 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.55
TTR P02766 1/20 0.54
JUN P05412 1/20 0.51
NFKB1 P19838 1/20 0.51
POLB P06746 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11005310 0.86 ALDH1A1 (0.72) ALDH1A1TSHRKDM4EMAPTFDPS
SCHEMBL15772745 0.86 ALDH1A1 (0.72) ALDH1A1TSHRKDM4EMAPTFDPS
SCHEMBL6552898 0.85 ALDH1A1 (0.70) ALDH1A1TSHRKDM4EMAPTFDPS
SCHEMBL29738486 0.85 ALDH1A1 (0.70) ALDH1A1TSHRKDM4EMAPTFDPS
SCHEMBL81717 0.85 ALDH1A1 (0.70) ALDH1A1TSHRKDM4EMAPTFDPS
SCHEMBL24529729 0.84 ALDH1A1 (0.64) ALDH1A1TSHRKDM4EMAPTFDPS
SCHEMBL28659385 0.84 POLB (0.61) ALDH1A1KDM4EMAPTHPGDSMN1; SMN2
SCHEMBL11663187 0.84 ALDH1A1 (0.64) ALDH1A1TSHRKDM4EMAPTFDPS
SCHEMBL11001189 0.83 ALDH1A1 (0.68) ALDH1A1TSHRKDM4EMAPTFDPS
SCHEMBL20394101 0.83 ALDH1A1 (0.68) ALDH1A1TSHRKDM4EMAPTFDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed