Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GRM6 | O15303 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4643313 | 0.89 | CYP3A4 (0.50) | CYP3A4TDP1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL4639908 | 0.83 | ALDH1A1 (0.43) | CYP3A4TDP1ALDH1A1LMNAESR1 | |
| SCHEMBL4644056 | 0.81 | CYP3A4 (0.46) | CYP3A4TDP1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL7170533 | 0.75 | KDM4E (0.44) | CYP3A4SMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL22423696 | 0.72 | ALDH1A1 (0.58) | CYP3A4TDP1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL4641134 | 0.72 | TSHR (0.41) | CYP3A4TDP1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL10722726 | 0.71 | CYP3A4 (0.81) | CYP3A4TDP1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL10455858 | 0.71 | CYP3A4 (0.59) | CYP3A4TDP1SMN1; SMN2ALDH1A1NR1H2 | |
| Phosphine SCHEMBL27595810 | 0.71 | ESR1 (0.53) | CYP3A4TDP1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL4640564 | 0.71 | ALDH1A1 (0.58) | CYP3A4TDP1SMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1120391-B1 | MOLECULAR COMPOUNDS CONTAINING NOVEL CARBOXYLIC ACID DERIVATIVES AS THE CONSTITUENT COMPOUND | NIPPON SODA CO (JP) | 2008-08-06 | — | — | EP | disclosed |
| US-6566548-B1 | Alkylene- or phenylene- tetrabenzoic acids and derivatives | NIPPON SODA CO., LTD. (JP) | 2003-05-20 | — | — | US | disclosed |
| EP-1120391-A1 | MOLECULAR COMPOUNDS CONTAINING NOVEL CARBOXYLIC ACID DERIVATIVES AS THE CONSTITUENT COMPOUND | NIPPON SODA CO., LTD. (JP) | 2001-08-01 | — | — | EP | disclosed |