Ethane

Ethane

SCHEMBL4643475

C.CC.CC.N.NC(O)=S.NC(O)=S

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.42
ATM Q13315 1/20 0.42
ATR Q13535 1/20 0.42
ALDH1A1 P00352 2/20 0.31
HSD17B10 Q99714 2/20 0.31
PTGS2 P35354 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethane SCHEMBL9345735 0.95 TSHR (0.46) TSHRATMATRALDH1A1HSD17B10
Ethane SCHEMBL11636383 0.95 TSHR (0.46) TSHRATMATRALDH1A1HSD17B10
Ethane SCHEMBL7082834 0.95 TSHR (0.46) TSHRATMATRALDH1A1HSD17B10
Methane SCHEMBL2373217 0.91 TSHR (0.50) TSHRATMATRALDH1A1HSD17B10
Ethane SCHEMBL667631 0.91 TSHR (0.50) TSHRATMATRALDH1A1HSD17B10
Methane SCHEMBL6566662 0.91 TSHR (0.50) TSHRATMATRALDH1A1HSD17B10
Ethane SCHEMBL5689604 0.91 TSHR (0.50) TSHRATMATRALDH1A1HSD17B10
Ethane SCHEMBL29145655 0.91 TSHR (0.50) TSHRATMATRALDH1A1HSD17B10
Ethane SCHEMBL4087796 0.86 TSHR (0.46) TSHRATMATRALDH1A1HSD17B10
Ethane SCHEMBL11775118 0.86 TSHR (0.46) TSHRATMATRALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0743353-B2 Additive combinations for lubricants and functional fluids LUBRIZOL CORP (US) 2008-08-06 EP disclosed
EP-0743353-B1 Additive combinations for lubricants and functional fluids LUBRIZOL CORP (US) 2003-01-02 EP disclosed
EP-0787791-B1 Functional fluid compositions having improved frictional and anti-oxidation properties LUBRIZOL CORP (US) 2002-12-18 EP disclosed
US-6365558-B2 POUR POINT DEPRESSANT AND POSSIBLY A PERFORMANCE ADDITIVE; ENVIRONMENTALLY FRIENDLY BASE FLUIDS IN INDUSTRIAL APPLICATIONS THE LUBRIZOL CORPORATION 2002-04-02 US disclosed
EP-0604125-B1 Pour point depressants for high monounsaturated vegetable oils and for high monounsaturated vegetable oils/biodegradable base and fluid mixtures LUBRIZOL CORP (US) 2002-03-13 EP disclosed
US-20010056045-A1 VEGETABLE OILS CONTAINING STYRENE/BUTADIENE COPOLYMERS IN COMBINATION WITH ADDITIONAL COMMERCIAL POLYMERS THAT HAVE GOOD LOW TEMPERATURE AND HIGH TEMPERATURE VISCOMETRICS LUBRIZOL CORPORATION, THE 2001-12-27 US disclosed
EP-0554421-B1 THE USE OF FUNCTIONALS FLUIDS COMPRISING TRIGLYCERIDES AND VARIOUS ADDITIVES AS TRACTOR OILS LUBRIZOL CORP (US) 2001-12-05 EP disclosed
EP-0602981-B1 Environmentally friendly viscosity index improving compositions LUBRIZOL CORP (US) 2000-03-15 EP disclosed
EP-0747466-B1 Vegetable oils containing styrene/butadiene copolymers in combination with additional commercial polymers that have good low temperature and high temperature viscometrics LUBRIZOL CORP (US) 2000-02-09 EP disclosed
EP-0626442-B1 Pour point depressant treated fatty acid esters as biodegradable, combustion engine fuels LUBRIZOL CORP (US) 1999-07-14 EP disclosed
US-4654403-A ADDITIVES IN TRANSMISSION AND HYDRAULIC FLUIDS THE LUBRIZOL CORPORATION (US) 1987-03-31 US disclosed
US-4604221-A Nitrogen-containing esters and lubricants containing them THE LUBRIZOL CORPORATION (US) 1986-08-05 US disclosed
US-4594378-A Blend of oil soluble homopolymer of non-aromatic mono-olefin and nitrogen-containing ester of a carboxy containing interpolymer THE LUBRIZOL CORPORATION (US) 1986-06-10 US disclosed
EP-0002286-B1 LUBRICANT OR FUEL ROHM AND HAAS COMPANY (US) 1984-07-04 EP disclosed
US-4411804-A CONTAINING GRAPHITE, MOLYBDENUM DISULFIDE, OR ZINC OXIDE AND FLOW CONTROL AGENT ATLANTIC RICHFIELD COMPANY (US) 1983-10-25 US disclosed
US-4292185-A COMPRISING A DIENE-MODIFIED MONOOLEFINIC POLYMER REACTED WITH CHLOROSULFONYL ISOCYANATE AND THEN WITH AN AMINE ROHM AND HAAS COMPANY (US) 1981-09-29 US disclosed
US-4160739-A Polyolefinic copolymer additives for lubricants and fuels ROHM AND HAAS COMPANY (US) 1979-07-10 US disclosed
EP-0002286-A2 Lubricant or fuel ROHM AND HAAS COMPANY (US) 1979-06-13 EP disclosed
US-4136040-A ALSO INCLUDING A NITROGEN CONTAINING MIXED ESTER OF AN OLEFIN ALPHA, B-UNSATURATED ACID OR ANHYDRIDE COPOLYMER ATLANTIC RICHFIELD COMPANY (US) 1979-01-23 US disclosed
US-3933761-A INTERPOLYMERS THE LUBRIZOL CORPORATION (US) 1976-01-20 US disclosed