Ethane

Ethane

SCHEMBL667631

CC.CC.NC(O)=S.NC(O)=S

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.50
ATM Q13315 1/20 0.50
ATR Q13535 1/20 0.50
ALDH1A1 P00352 2/20 0.36
HSD17B10 Q99714 2/20 0.36
PTGS2 P35354 1/20 0.36
HPGD P15428 1/20 0.36
ACHE P22303 1/20 0.33
TAS2R38 P59533 1/20 0.32
LMNA P02545 1/20 0.31
ALOX15 P16050 1/20 0.31
BLM P54132 1/20 0.31
PMP22 Q01453 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethane SCHEMBL5689604 1.00 TSHR (0.50) TSHRATMATRALDH1A1HSD17B10
Ethane SCHEMBL29145655 1.00 TSHR (0.50) TSHRATMATRALDH1A1HSD17B10
Ethane SCHEMBL4087796 0.95 TSHR (0.46) TSHRATMATRALDH1A1HSD17B10
Ethane SCHEMBL9345735 0.95 TSHR (0.46) TSHRATMATRALDH1A1HSD17B10
Ethane SCHEMBL11775118 0.95 TSHR (0.46) TSHRATMATRALDH1A1HSD17B10
Ethane SCHEMBL9748577 0.95 TSHR (0.46) TSHRATMATRALDH1A1HSD17B10
Ethane SCHEMBL1223967 0.95 TSHR (0.46) TSHRATMATRALDH1A1HSD17B10
Ethane SCHEMBL7082834 0.95 TSHR (0.46) TSHRATMATRALDH1A1HSD17B10
Ethane SCHEMBL11636383 0.95 TSHR (0.46) TSHRATMATRALDH1A1HSD17B10
Ethane SCHEMBL1879942 0.95 TSHR (0.46) TSHRATMATRALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 240 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3787631-B1 MODULATORS OF ORPHAN NUCLEAR RECEPTORS FOR NASH AND OTHER METABOLIC DISORDERS UNIV EMORY (US) 2025-09-10 EP claimed
EP-4255414-B1 COMPOSITION CONTAINING RANITIDINE HAVING A LOW IRON CONTENT OPELLA HEALTHCARE GROUP SAS (FR) 2025-02-05 EP claimed
US-20240024278-A1 COMPOSITION CONTAINING RANITIDINE HAVING A LOW IRON CONTENT SANOFI CHIMIE (FR) 2024-01-25 US claimed
CN-116887824-A Compositions containing ranitidine with low iron content 欧彼乐医疗集团公司 2023-10-13 CN claimed
EP-4255414-A1 COMPOSITION CONTAINING RANITIDINE HAVING A LOW IRON CONTENT Opella Healthcare Group SAS (FR) 2023-10-11 EP claimed
EP-3976878-B1 METHODS OF MAKING A DEFLECTION MEMBER PROCTER & GAMBLE (US) 2023-07-05 EP claimed
WO-2022117771-A1 COMPOSITION CONTAINING RANITIDINE HAVING A LOW IRON CONTENT OPELLA HEALTHCARE GROUP SAS (FR) 2022-06-09 WO claimed
EP-3787631-A1 MODULATORS OF ORPHAN NUCLEAR RECEPTORS FOR NASH AND OTHER METABOLIC DISORDERS Emory University (US) 2021-03-10 EP claimed
US-20210052603-A1 MODULATORS OF ORPHAN NUCLEAR RECEPTORS FOR NASH AND OTHER METABOLIC DISORDERS EMORY UNIVERSITY 2021-02-25 US claimed
EP-1742993-B1 RUBBER COMPOSITION AND TIRE COMPRISING SAME MICHELIN & CIE (FR) 2018-07-04 EP claimed
EP-1660078-A1 USE OF INDOMETHACIN AND DERIVATIVES AS BROAD-SPECTRUM ANTIVIRAL DRUGS AND CORRESPONDING PHARMACEUTICAL COMPOSITIONS. Università degli Studi di Roma " Tor Vergata" (IT) 2006-05-31 EP claimed
JP-2006514917-A 2006-05-18 JP claimed
EP-1581167-A2 COMPOSITIONS AND METHODS FOR THE TREATMENT OF PARKINSON'S DISEASE AND TARDIVE DYSKINESIAS Alpha Research Group, LLC (US) 2005-10-05 EP claimed
WO-2005013980-A1 USE OF INDOMETHACIN AND DERIVATIVES AS BROAD-SPECTRUM ANTIVIRAL DRUGS AND CORRESPONDING PHARMACEUTICAL COMPOSITIONS. UNIVERSITA' DEGLI STUDI DI ROMA 'TOR VERGATA' (IT) 2005-02-17 WO claimed
US-20040229908-A1 Compositions and methods for the treatment of Parkinson's disease and tardive dyskinesias Greenlee, Winner and Sullivan, P.C. 2004-11-18 US claimed
WO-2004004660-A2 COMPOSITIONS AND METHODS FOR THE TREATMENT OF PARKINSON’S DISEASE AND TARDIVE DYSKINESIAS ALPHA RESEARCH GROUP, L.L.C. (US) 2004-01-15 WO claimed
US-20020198231-A1 Compositions and methods for the treatment of Parkinson's disease Greenlee, Winner and Sullivan, P.C. 2002-12-26 US claimed
WO-1997009976-A2 METHOD OF REDUCING NEUROTOXIC INJURY WITH ZINC CHELATORS WASHINGTON UNIVERSITY (CH) 1997-03-20 WO claimed
EP-0152253-B1 METHOD FOR THE DETERMINATION OF CERULOPLASMIN ACTIVITY IN A SAMPLE Kyowa Medex Co. Ltd. (JP) 1991-10-16 EP claimed
WO-1989002430-A1 NEW CHOLINE COMPOUND, METHOD FOR ITS PREPARATION AND NEW DRUGS CONTAINING IT LAFON PHARMA S.A. (CH) 1989-03-23 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210052603-A1 MODULATORS OF ORPHAN NUCLEAR RECEPTORS FOR NASH AND OTHER METABOLIC DISORDERS RORA, RORB, RORC TSHR 244/4885ATM 2774/4885ATR 3279/4885
US-20240024278-A1 COMPOSITION CONTAINING RANITIDINE HAVING A LOW IRON CONTENT TFRC, HAMP, HRH2 TSHR 2722/4885ATM 4882/4885ATR 4605/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.