SCHEMBL4643498

SCHEMBL4643498

COC(=O)/C=C\C(=O)OCC(=O)Oc1ccc(OC)cc1

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.53
LMNA P02545 3/20 0.53
KMT2A Q03164 3/20 0.47
MEN1 O00255 1/20 0.47
TDP1 Q9NUW8 2/20 0.47
ALDH1A1 P00352 2/20 0.46
MAPT P10636 1/20 0.46
HTT P42858 1/20 0.46
HSD17B10 Q99714 1/20 0.46
KDM4E B2RXH2 3/20 0.45
RAB9A P51151 1/20 0.45
GSK3B P49841 1/20 0.45
CASP3 P42574 1/20 0.43
SENP7 Q9BQF6 1/20 0.43
SENP6 Q9GZR1 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4643506 1.00 GAA (0.53) GAALMNAKMT2AMEN1TDP1
SCHEMBL4647011 1.00 GAA (0.53) GAALMNAKMT2AMEN1TDP1
SCHEMBL4644743 0.89 CA12 (0.49) GAALMNAKMT2AMEN1ALDH1A1
SCHEMBL4644389 0.89 GAA (0.55) GAALMNAKMT2AMEN1TDP1
SCHEMBL4644394 0.89 GAA (0.55) GAALMNAKMT2AMEN1TDP1
SCHEMBL4644628 0.89 GAA (0.55) GAALMNAKMT2AMEN1TDP1
SCHEMBL4647565 0.89 CA12 (0.49) GAALMNAKMT2AMEN1ALDH1A1
SCHEMBL4644739 0.89 CA12 (0.49) GAALMNAKMT2AMEN1ALDH1A1
SCHEMBL4643443 0.88 MAPT (0.44) GAALMNAKMT2AMEN1ALDH1A1
SCHEMBL4644946 0.88 MAPT (0.44) GAALMNAKMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed