SCHEMBL4644743

SCHEMBL4644743

COC(=O)C=CC(=O)OCC(=O)Oc1ccc(O)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.49
CA1 P00915 2/20 0.49
CA2 P00918 2/20 0.49
CA7 P43166 2/20 0.49
CA9 Q16790 2/20 0.49
CA14 Q9ULX7 2/20 0.49
TYR P14679 2/20 0.49
MAPT P10636 4/20 0.45
ALDH1A1 P00352 3/20 0.45
LMNA P02545 2/20 0.45
KMT2A Q03164 2/20 0.45
HSD17B10 Q99714 2/20 0.45
HTT P42858 1/20 0.45
GAA P10253 1/20 0.41
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
TP53 P04637 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4647565 1.00 CA12 (0.49) CA12CA1CA2CA7CA9
SCHEMBL4644739 1.00 CA12 (0.49) CA12CA1CA2CA7CA9
SCHEMBL4643506 0.89 GAA (0.53) MAPTALDH1A1LMNAKMT2AHSD17B10
SCHEMBL4643498 0.89 GAA (0.53) MAPTALDH1A1LMNAKMT2AHSD17B10
SCHEMBL4647011 0.89 GAA (0.53) MAPTALDH1A1LMNAKMT2AHSD17B10
SCHEMBL4642198 0.88 CA12 (0.56) CA12CA1CA2CA7CA9
SCHEMBL4641363 0.88 CA12 (0.56) CA12CA1CA2CA7CA9
SCHEMBL4641366 0.88 CA12 (0.56) CA12CA1CA2CA7CA9
SCHEMBL4644946 0.87 MAPT (0.44) MAPTALDH1A1LMNAKMT2AHSD17B10
SCHEMBL4643443 0.87 MAPT (0.44) MAPTALDH1A1LMNAKMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed