SCHEMBL4643872

SCHEMBL4643872

[CH2]CCC(=O)Oc1ccc(Br)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.50
MAPT P10636 4/20 0.50
ALDH1A1 P00352 2/20 0.50
HTT P42858 2/20 0.50
LMNA P02545 2/20 0.50
HSD17B10 Q99714 1/20 0.50
MEN1 O00255 2/20 0.45
MGLL Q99685 1/20 0.41
BCL9 O00512 1/20 0.40
CTNNB1 P35222 1/20 0.40
LDHA P00338 1/20 0.40
KDM4E B2RXH2 1/20 0.39
HPGD P15428 1/20 0.39
FFAR1 O14842 1/20 0.39
FFAR4 Q5NUL3 1/20 0.39
MAPK1 P28482 1/20 0.39
RAB9A P51151 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
RXFP1 Q9HBX9 1/20 0.39
ESR1 P03372 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4646070 0.91 KMT2A (0.51) KMT2AMAPTALDH1A1HTTLMNA
SCHEMBL4642695 0.84 KMT2A (0.44) KMT2AMAPTALDH1A1HTTLMNA
SCHEMBL4642216 0.82 KMT2A (0.52) KMT2AMAPTALDH1A1HTTLMNA
SCHEMBL2004570 0.82 KMT2A (0.52) KMT2AMAPTALDH1A1HTTLMNA
SCHEMBL4642464 0.81 KMT2A (0.50) KMT2AMAPTALDH1A1HTTLMNA
SCHEMBL4644295 0.81 KMT2A (0.60) KMT2AMAPTALDH1A1HTTLMNA
SCHEMBL11654682 0.81 KMT2A (0.50) KMT2AMAPTALDH1A1HTTLMNA
SCHEMBL4732 0.81 BCL9 (0.60) KMT2AMAPTALDH1A1HTTLMNA
SCHEMBL15567082 0.80 KMT2A (0.46) KMT2AMAPTALDH1A1HTTLMNA
SCHEMBL3252190 0.80 PRSS1 (0.54) KMT2AMAPTALDH1A1HTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed