SCHEMBL4732

SCHEMBL4732

CCCC(=O)Oc1ccc(Br)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL9 O00512 1/20 0.60
CTNNB1 P35222 1/20 0.60
KMT2A Q03164 11/20 0.55
ALDH1A1 P00352 3/20 0.55
MAPT P10636 3/20 0.55
LMNA P02545 2/20 0.55
HTT P42858 1/20 0.55
HSD17B10 Q99714 1/20 0.55
MGLL Q99685 1/20 0.51
KDM4E B2RXH2 1/20 0.47
GLA P06280 1/20 0.47
GAA P10253 1/20 0.47
ESR1 P03372 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
HIF1A Q16665 2/20 0.46
RAB9A P51151 2/20 0.46
RECQL P46063 1/20 0.46
MEN1 O00255 2/20 0.45
MAPK1 P28482 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11023644 0.90 BCL9 (0.70) BCL9CTNNB1KMT2AALDH1A1MAPT
SCHEMBL27750475 0.89 MGLL (0.56) BCL9CTNNB1KMT2AALDH1A1MAPT
SCHEMBL8674996 0.87 MGLL (0.59) BCL9CTNNB1KMT2AALDH1A1MAPT
SCHEMBL7808700 0.86 MGLL (0.61) BCL9CTNNB1KMT2AALDH1A1MAPT
SCHEMBL1821398 0.84 KMT2A (0.63) KMT2AALDH1A1MAPTLMNAHTT
SCHEMBL6836918 0.84 BCL9 (0.64) BCL9CTNNB1KMT2AALDH1A1MAPT
SCHEMBL4642216 0.82 KMT2A (0.52) BCL9CTNNB1KMT2AALDH1A1MAPT
SCHEMBL2292825 0.82 BCL9 (0.62) BCL9CTNNB1KMT2AALDH1A1MAPT
SCHEMBL8765721 0.82 BCL9 (0.62) BCL9CTNNB1KMT2AALDH1A1MAPT
SCHEMBL898796 0.82 BCL9 (0.62) BCL9CTNNB1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101380317-B Pharmaceutical composition for relieving pruritus CAYMAN ISLAND SHANGANSHENG DEV PHARMACEUTICAL CO LTD 2010-12-08 CN claimed
CN-101380317-A Pharmaceutical composition for relieving pruritus CAYMAN ISLAND SHANGANSHENG DEV (CN) 2009-03-11 CN claimed
US-12435181-B2 Formulations capable of reacting with or removal of molecular oxygen LI SHENSHEN (US) 2025-10-07 US disclosed
CN-117417285-B Isomanka key intermediate and preparation method thereof 苏中药业集团股份有限公司 2025-04-25 CN disclosed
CN-118930560-A Bifunctional degradation agents for hematopoietic progenitor cell kinases and therapeutic uses thereof 新锐思生物制药股份有限公司 2024-11-12 CN disclosed
EP-3614113-B1 TEMPERATURE DETECTING MATERIAL AND PRODUCT CONTROL METHOD HITACHI INDUSTRY EQUIPMENT SYSTEMS CO LTD (JP) 2024-07-17 EP disclosed
US-11933677-B2 Temperature detecting material, temperature detecting ink using same, temperature indicator, and product control system HITACHI INDUSTRIAL EQUIPMENT SYSTEMS CO., LTD. (JP) 2024-03-19 US disclosed
CN-117417285-A Isomanka key intermediate and preparation method thereof 苏中药业集团股份有限公司 2024-01-19 CN disclosed
CN-117209560-A Diagnosis and treatment integrated PSMA double-ligand compound and application thereof 南方医科大学南方医院 2023-12-12 CN disclosed
EP-4267633-A1 LOW DISPERSITY POLYMERS AS A RESULT OF NEAR INFRARED LIGHT INITIATION AND AN IRON CATALYST Phosuma Photonic & Sustainable Materials GmbH (DE) 2023-11-01 EP disclosed
CN-113899907-B Method for efficiently screening aflatoxin green prevention and control materials in one step and application thereof 中国农业科学院油料作物研究所 2023-06-27 CN disclosed
WO-1996040681-A1 N-HETEROARYL-PYRIDINESULFONAMIDE DERIVATIVES AND THEIR USE AS ENDOTHELIN ANTAGONISTS ZENECA LIMITED (GB) 1996-12-19 WO disclosed
EP-0705284-A1 PROCESS FOR THE PREPARATION OF LOW MOLECULAR WEIGHT COPOLYMERS OF ETHYLENE WITH AT LEAST ONE OTHER 1-ALKENE DSM NV (NL) 1996-04-10 EP disclosed
EP-0696284-A1 HETEROCYCLIC DERIVATIVES ZENECA LIMITED (GB) 1996-02-14 EP disclosed
WO-1995029682-A1 BINDING OF E-SELECTIN, P-SELECTIN OR L-SELECTIN TO SIALYL-LEWISx OR SIALYL-LEWIS?a¿ TEXAS BIOTECHNOLOGY CORPORATION (US) 1995-11-09 WO disclosed
WO-1995000564-A1 PROCESS FOR THE PREPARATION OF LOW MOLECULAR WEIGHT COPOLYMERS OF ETHYLENE WITH AT LEAST ONE OTHER 1-ALKENE DSM N.V. (NL) 1995-01-05 WO disclosed
WO-1994025459-A1 HETEROCYCLIC DERIVATIVES ZENECA LIMITED (GB) 1994-11-10 WO disclosed
EP-0044119-B1 PROCESS FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE WITH AT LEAST ONE OTHER 1-ALKENE STAMICARBON B.V. (NL) 1985-05-29 EP disclosed
US-4435552-A COORDINATION CATALYST CONTAINING HALOACYL COMPOUND STAMICARBON B.V. (NL) 1984-03-06 US disclosed
EP-0044119-A2 Process for the preparation of copolymers of ethylene with at least one other 1-alkene STAMICARBON B.V. (NL) 1982-01-20 EP disclosed