SCHEMBL4643953

SCHEMBL4643953

COc1ccccc1OC(=O)CO

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.57
ALDH1A1 P00352 2/20 0.57
L3MBTL1 Q9Y468 2/20 0.55
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA4 P22748 1/20 0.52
CA7 P43166 1/20 0.52
CA9 Q16790 1/20 0.52
CA14 Q9ULX7 1/20 0.52
POLB P06746 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
KMT2A Q03164 3/20 0.50
MEN1 O00255 2/20 0.50
ATM Q13315 2/20 0.49
TDP1 Q9NUW8 1/20 0.49
LMNA P02545 3/20 0.49
CYP1A2 P05177 2/20 0.49
AGTR1 P30556 1/20 0.49
KDM4E B2RXH2 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27852383 0.98 MAPT (0.55) MAPTALDH1A1L3MBTL1CA12CA1
SCHEMBL3361882 0.86 KMT2A (0.59) MAPTALDH1A1L3MBTL1CA12CA1
SCHEMBL3105452 0.86 MAPT (0.58) MAPTALDH1A1L3MBTL1CA12CA1
SCHEMBL4642495 0.85 KMT2A (0.55) MAPTALDH1A1L3MBTL1CA12CA1
SCHEMBL30883175 0.84 MAPT (0.57) MAPTALDH1A1L3MBTL1CA12CA1
SCHEMBL362210 0.84 MAPT (0.57) MAPTALDH1A1L3MBTL1CA12CA1
SCHEMBL1171372 0.83 L3MBTL1 (0.60) MAPTALDH1A1L3MBTL1POLBSMN1; SMN2
SCHEMBL30233793 0.83 L3MBTL1 (0.60) MAPTALDH1A1L3MBTL1POLBSMN1; SMN2
SCHEMBL6984154 0.82 MAPT (0.55) MAPTALDH1A1L3MBTL1CA12CA1
SCHEMBL9615762 0.82 MAPT (0.55) MAPTALDH1A1L3MBTL1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101854907-B Cosmetic composition comprising hydroxymethionine and 3-aminopropanesulfonic acid SEDERMA SA 2014-06-18 CN disclosed
CN-102802601-A Cosmetic use of tyr-arg dipeptide to combat cutaneous sagging SEDERMA SA 2012-11-28 CN disclosed
CN-101854907-A Cosmetic composition comprising hydroxymethionine and 3-aminopropanesulfonic acid SEDERMA SA 2010-10-06 CN disclosed
CN-101376622-A Method for synthesizing vanillic aldehyde from mandelic acid with cuprous oxide as catalyst UNIV BEIJING CHEMICAL (CN) 2009-03-04 CN disclosed
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed