Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.40 |
| ▸ | MDM4 | O15151 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4642731 | 0.91 | MAPT (0.43) | MAPTLMNAMDM2MDM4PTGS2 | |
| SCHEMBL4641582 | 0.90 | SRC (0.39) | MAPTALDH1A1MAPK1KMT2A | |
| SCHEMBL4642022 | 0.85 | LMNA (0.36) | MAPTLMNAMDM2MDM4NPC1 | |
| SCHEMBL4643871 | 0.82 | MAPT (0.47) | MAPTLMNAMDM2MDM4PTGS2 | |
| SCHEMBL4644585 | 0.80 | SRC (0.40) | MAPTLMNAMDM2MDM4ALDH1A1 | |
| SCHEMBL4645849 | 0.71 | HCAR2 (0.41) | MAPTLMNAMDM2MDM4RAB9A | |
| SCHEMBL4643564 | 0.71 | MAPT (0.43) | MAPTLMNAMDM2MDM4PTGS2 | |
| SCHEMBL4643595 | 0.71 | MAPT (0.44) | MAPTLMNAMDM2MDM4PTGS2 | |
| SCHEMBL4642012 | 0.70 | MEN1 (0.41) | MAPTLMNANPC1RAB9AALDH1A1 | |
| Diethyl Maleate SCHEMBL11324124 | 0.70 | MAPT (0.60) | MAPTLMNAMDM2MDM4PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487928-B1 | FILM-FORMING POLYMER AND ANTIFOULING PAINT | JOTUN AS (NO) | 2008-08-13 | — | — | EP | disclosed |
| EP-1487928-A1 | FILM-FORMING POLYMER AND ANTIFOULING PAINT | Jotun AS (NO) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003080747-A1 | FILM-FORMING POLYMER AND ANTIFOULING PAINT | JOTUN AS (NO) | 2003-10-02 | — | — | WO | disclosed |