SCHEMBL4644113

SCHEMBL4644113

O=C(CCCCCl)Oc1c(Cl)cc(Br)cc1Cl

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.37
KDM4E B2RXH2 5/20 0.35
MAPT P10636 1/20 0.33
ALDH1A1 P00352 3/20 0.33
PYGL P06737 1/20 0.33
LMNA P02545 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
KMT2A Q03164 4/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MEN1 O00255 3/20 0.32
TSHR P16473 2/20 0.32
VCAM1 P19320 1/20 0.32
RECQL P46063 1/20 0.31
PLAU P00749 1/20 0.31
NPY1R P25929 1/20 0.31
NPY2R P49146 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4642019 0.95 POLB (0.38) POLBKDM4EMAPTALDH1A1LMNA
SCHEMBL4645432 0.92 KDM4E (0.39) POLBKDM4EALDH1A1LMNATDP1
SCHEMBL4642401 0.88 POLB (0.37) POLBKDM4EALDH1A1LMNAKMT2A
SCHEMBL4643853 0.88 KDM4E (0.39) POLBKDM4EALDH1A1LMNATDP1
SCHEMBL4647539 0.87 VCAM1 (0.42) POLBKDM4EMAPTALDH1A1LMNA
SCHEMBL4644695 0.87 MAPT (0.41) KDM4EMAPTALDH1A1PYGLLMNA
SCHEMBL4644580 0.85 VCAM1 (0.41) POLBKDM4EMAPTALDH1A1LMNA
SCHEMBL4642344 0.85 HSD17B10 (0.37) KDM4EKMT2AVCAM1
SCHEMBL4644489 0.84 POLB (0.35) POLBKDM4EMAPTALDH1A1LMNA
SCHEMBL27619991 0.84 POLB (0.35) POLBKDM4EMAPTALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed