Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.78 |
| ▸ | HPGD | P15428 | 3/20 | 0.78 |
| ▸ | HTR1A | P08908 | 2/20 | 0.78 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.78 |
| ▸ | HTR2C | P28335 | 1/20 | 0.78 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.55 |
| ▸ | TUBB | P07437 | 2/20 | 0.55 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.55 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.55 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.55 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.55 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.55 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5573107 | 1.00 | KDM4E (0.78) | KDM4EALDH1A1HPGDHTR1AHSD17B10 | |
| SCHEMBL25308221 | 0.90 | KDM4E (0.64) | KDM4EALDH1A1HPGDHTR1AHSD17B10 | |
| SCHEMBL9247970 | 0.90 | KDM4E (0.63) | KDM4EALDH1A1HPGDHTR1AHSD17B10 | |
| SCHEMBL9247967 | 0.90 | KDM4E (0.63) | KDM4EALDH1A1HPGDHTR1AHSD17B10 | |
| Sinapic Acid Methyl Ether SCHEMBL207442 | 0.88 | KDM4E (1.00) | KDM4EALDH1A1HPGDHTR1AHSD17B10 | |
| Sinapic Acid Methyl Ether SCHEMBL207441 | 0.88 | KDM4E (1.00) | KDM4EALDH1A1HPGDHTR1AHSD17B10 | |
| SCHEMBL4651382 | 0.87 | PKM (0.78) | KDM4EALDH1A1HPGDHTR1AHSD17B10 | |
| SCHEMBL5573125 | 0.86 | KDM4E (0.59) | KDM4EALDH1A1HPGDHTR1AHSD17B10 | |
| SCHEMBL5573123 | 0.86 | KDM4E (0.59) | KDM4EALDH1A1HPGDHTR1AHSD17B10 | |
| Sinapic Acid Methyl Ether SCHEMBL9848210 | 0.86 | KDM4E (0.96) | KDM4EALDH1A1HPGDHTR1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61093171-A | — | — | None | — | — | JP | disclosed |
| JP-61072773-A | — | — | None | — | — | JP | disclosed |
| WO-2023131362-A1 | PHENYLPROPANOID DERIVATIVES | USTAV EXPERIMENTALNI BOTANIKY AV ČR, V. V. I. (CZ) | 2023-07-13 | — | — | WO | disclosed |
| EP-2519511-B1 | NOVEL PIPERINE DERIVATIVES AS GABA-A RECEPTORS MODULATORS | Universität Wien (AT) | 2015-12-16 | — | — | EP | disclosed |
| WO-2011080313-A1 | NOVEL PIPERINE DERIVATIVES AS GABA - A RECEPTORS MODULATORS | Universität Wien (AT) | 2011-07-07 | — | — | WO | disclosed |
| EP-0934924-B1 | NOVEL DIAMIDE COMPOUNDS AND DRUGS CONTAINING THE SAME | KOWA CO (JP) | 2008-08-13 | — | — | EP | disclosed |
| EP-1057815-B1 | CYCLIC AMIDE COMPOUNDS | KOWA CO (JP) | 2007-09-05 | — | — | EP | disclosed |
| US-6828316-B2 | Antiallergens | KOWA CO., LTD. (JP) | 2004-12-07 | — | — | US | disclosed |
| US-6645957-B2 | Useful in preventing and treating allergic immunological diseases; treating asthma, atopic dermatitis, allergic rhinitis, inflammatory large bowel disease, contact dermatitis | KOWA CO., LTD. (JP) | 2003-11-11 | — | — | US | disclosed |
| US-6576642-B2 | Inhibitors of the production of Ig E antibodies, antiallergens | KOWA CO., LTD. (JP) | 2003-06-10 | — | — | US | disclosed |
| EP-0926138-A1 | DIAMIDE COMPOUNDS AND DRUGS CONTAINING THE SAME | KOWA CO. LTD. (JP) | 1999-06-30 | — | — | EP | disclosed |
| EP-0236227-B1 | NITRATE DERIVATIVES AND THEIR USE AS VASODILATORS | TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) | 1989-12-13 | — | — | EP | disclosed |
| US-4792553-A | TREATMENT OF CARDIOVASCULAR AND CEREBROVASCULAR DISORDERS | TERUMO KABUSHIKI KAISHA (JP) | 1988-12-20 | — | — | US | disclosed |
| EP-0175331-B1 | PIPERAZINE DERIVATIVES | TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) | 1988-11-17 | — | — | EP | disclosed |
| US-4780560-A | Nitrate derivatives and vasodilators containing the same | TERUMO CORPORATION (JP) | 1988-10-25 | — | — | US | disclosed |
| EP-0236227-A1 | Nitrate derivatives and their use as vasodilators | TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) | 1987-09-09 | — | — | EP | disclosed |
| US-4656172-A | CONTROLLING OR PREVENTING CEREBRAL, CORONARY OR PERIPHIPHERAL VASCULAR DISORDER | TERUMO KABUSHIKI KAISHA (JP) | 1987-04-07 | — | — | US | disclosed |
| JP-S6193171-A | HOMOPIPERAZINE DERIVATIVE AND VASODILATOR CONTAINING SAME | TERUMO CORP | 1986-05-12 | — | — | JP | disclosed |
| JP-S6172773-A | PIPERAZINE DERIVATIVE AND VASODILATOR CONTAINING IT | TERUMO CORP | 1986-04-14 | — | — | JP | disclosed |
| EP-0175331-A1 | Piperazine Derivatives | TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) | 1986-03-26 | — | — | EP | disclosed |