SCHEMBL4644188

SCHEMBL4644188

CCCCCCCCCC(F)C(F)(F)[C](F)F

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.44
LMNA P02545 1/20 0.40
FAAH O00519 7/20 0.36
CES1 P23141 5/20 0.36
GPR84 Q9NQS5 3/20 0.36
CES2 O00748 3/20 0.36
FDPS P14324 3/20 0.36
MEN1 O00255 1/20 0.36
CYP1A2 P05177 1/20 0.36
KMT2A Q03164 1/20 0.36
HSD17B10 Q99714 1/20 0.36
SPHK1 Q9NYA1 1/20 0.36
FFAR1 O14842 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10689014 1.00 MAPT (0.44) MAPTLMNAFAAHCES1GPR84
SCHEMBL4229204 0.98 MAPT (0.41) MAPTLMNAFAAHCES1GPR84
SCHEMBL964507 0.91 ALDH1A1 (0.33) MAPTFAAHCES1CES2FDPS
SCHEMBL3369479 0.80 MAPT (0.55) MAPTFAAHCES1GPR84CES2
SCHEMBL3371707 0.80 MAPT (0.55) MAPTFAAHCES1GPR84CES2
SCHEMBL25269389 0.80 MAPT (0.55) MAPTFAAHCES1GPR84CES2
SCHEMBL3371132 0.80 MAPT (0.55) MAPTFAAHCES1GPR84CES2
SCHEMBL3367802 0.80 MAPT (0.55) MAPTFAAHCES1GPR84CES2
SCHEMBL3371518 0.80 MAPT (0.55) MAPTFAAHCES1GPR84CES2
SCHEMBL3365110 0.80 MAPT (0.55) MAPTFAAHCES1GPR84CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2975663-B1 ORGANIC ELECTRONIC ELEMENT COMPRISING FULLERENE DERIVATIVE LG CHEMICAL LTD (KR) 2020-08-12 EP disclosed
US-9711729-B2 Organic electronic element comprising fullerene derivative LG CHEM, LTD. (KR) 2017-07-18 US disclosed
US-20160087213-A1 ORGANIC ELECTRONIC ELEMENT COMPRISING FULLERENE DERIVATIVE LG CHEM, LTD. (KR) 2016-03-24 US disclosed
EP-2975663-A1 ORGANIC ELECTRONIC ELEMENT COMPRISING FULLERENE DERIVATIVE LG Chem, Ltd. (KR) 2016-01-20 EP disclosed
EP-1443042-B1 HYBRID ONIUM SALT WAKO PURE CHEM IND LTD (JP) 2008-08-13 EP disclosed
US-7101918-B2 Hybrid type onium salt WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2006-09-05 US disclosed
US-20050020710-A1 Hybrid onium salt WAKO PURE CHEMICALS INDUSTRIES, LTD. (JP) 2005-01-27 US disclosed
EP-1443042-A1 HYBRID ONIUM SALT Wako Pure Chemical Industries, Ltd. (JP) 2004-08-04 EP disclosed