SCHEMBL4644322

SCHEMBL4644322

CCOC(=O)CCc1ccc(OC(=O)CCO)c([N+](=O)[O-])c1

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 2/20 0.52
CYP4A11 Q02928 2/20 0.52
ALDH1A1 P00352 8/20 0.43
LMNA P02545 4/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
MAPT P10636 3/20 0.42
KDM4E B2RXH2 1/20 0.42
MITF O75030 1/20 0.40
GAA P10253 2/20 0.39
HTT P42858 1/20 0.39
MAPK1 P28482 1/20 0.39
CYP4Z1 Q86W10 1/20 0.39
TNF P01375 1/20 0.39
APP P05067 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4641790 0.93 CYP4F2 (0.50) CYP4F2CYP4A11ALDH1A1LMNASMN1; SMN2
SCHEMBL4644996 0.92 CYP4F2 (0.49) CYP4F2CYP4A11ALDH1A1LMNASMN1; SMN2
SCHEMBL4644934 0.92 CYP4F2 (0.50) CYP4F2CYP4A11ALDH1A1LMNASMN1; SMN2
SCHEMBL4642616 0.90 CYP4F2 (0.45) CYP4F2CYP4A11ALDH1A1LMNASMN1; SMN2
SCHEMBL4642309 0.88 CYP4F2 (0.46) CYP4F2CYP4A11ALDH1A1LMNAMAPT
SCHEMBL4643983 0.88 MAPT (0.44) CYP4F2CYP4A11ALDH1A1LMNASMN1; SMN2
SCHEMBL4641524 0.87 MAPT (0.43) CYP4F2CYP4A11ALDH1A1LMNAMAPT
SCHEMBL27601505 0.87 MAPT (0.43) CYP4F2CYP4A11ALDH1A1LMNASMN1; SMN2
SCHEMBL6794871 0.80 ALOX15 (0.50) ALDH1A1LMNASMN1; SMN2MAPTGAA
SCHEMBL4643463 0.80 CYP4F2 (0.52) CYP4F2CYP4A11ALDH1A1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100519671-C Film-forming polymer and antifouling paint JOTUN AS (NO) 2009-07-29 CN disclosed
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
CN-1643085-A Film-forming polymer and antifouling paint JOTUN AS (NO) 2005-07-20 CN disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed