SCHEMBL4644449

SCHEMBL4644449

CC(C)C[Si](CC(C)C)(CC(C)C)OC(=O)CO

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.30
CYP19A1 P11511 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4644643 0.83 CA12 (0.30)
SCHEMBL4644182 0.80 CA12 (0.31)
SCHEMBL4641809 0.80 TSHR (0.33) TSHR
SCHEMBL4641743 0.79 CAMK2A (0.33) TSHR
SCHEMBL4641879 0.78 CYP19A1 (0.34) CYP19A1
SCHEMBL4641511 0.78 LMNA (0.35) TSHR
SCHEMBL4641704 0.77
SCHEMBL4645192 0.77 TSHR (0.31) TSHR
SCHEMBL475931 0.76 TSHR (0.36) TSHR
SCHEMBL475928 0.74 TSHR (0.35) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed