SCHEMBL4644460

SCHEMBL4644460

CCC[CH]C(=O)Oc1ccc(Br)cc1C=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 2/20 0.52
HPGD P15428 3/20 0.42
ERN1 O75460 2/20 0.41
TSHR P16473 2/20 0.40
PLA2G1B P04054 1/20 0.38
ATG4B Q9Y4P1 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.37
POLB P06746 1/20 0.37
CTDSP1 Q9GZU7 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
ALDH1A1 P00352 4/20 0.36
MAPT P10636 4/20 0.36
KDM4E B2RXH2 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C19 P33261 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
KMT2A Q03164 3/20 0.35
GAA P10253 1/20 0.35
HTT P42858 1/20 0.35
TNFRSF1A P19438 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4644283 0.89 PTGDR2 (0.55) PTGDR2HPGDERN1TSHRPLA2G1B
SCHEMBL4644428 0.82 CREBBP (0.40) PTGDR2HPGDTSHRPOLBTDP1
SCHEMBL4644034 0.82 KDM4E (0.50) ERN1L3MBTL1TDP1ALDH1A1KDM4E
SCHEMBL4646084 0.81 PTGDR2 (0.55) PTGDR2HPGDERN1TSHRPLA2G1B
SCHEMBL4642014 0.81 PTGDR2 (0.49) PTGDR2HPGDERN1TDP1ALDH1A1
SCHEMBL28464660 0.78 PTGDR2 (0.55) PTGDR2HPGDERN1TSHRL3MBTL1
SCHEMBL4647606 0.78 ERN1 (0.41) PTGDR2HPGDERN1TDP1ALDH1A1
SCHEMBL2879911 0.77 PTGDR2 (0.58) PTGDR2HPGDERN1TSHRL3MBTL1
SCHEMBL4646065 0.76 MGLL (0.49) L3MBTL1MAPTCYP1A2CYP2C19KMT2A
SCHEMBL4647217 0.75 PTGDR2 (0.59) PTGDR2HPGDERN1TSHRPLA2G1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed