⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7370219 | 0.97 | TSHR (0.43) | — | |
| SCHEMBL14567834 | 0.84 | RECQL (0.55) | — | |
| SCHEMBL28550238 | 0.82 | — | — | |
| SCHEMBL17449665 | 0.80 | — | — | |
| SCHEMBL19090735 | 0.80 | — | — | |
| SCHEMBL423404 | 0.80 | LMNA (0.42) | — | |
| SCHEMBL8214479 | 0.78 | TSHR (0.40) | — | |
| SCHEMBL19133996 | 0.78 | TSHR (0.40) | — | |
| SCHEMBL20928615 | 0.78 | CA14 (0.45) | — | |
| Hydrochloric Acid SCHEMBL21629430 | 0.78 | LMNA (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3240543-B1 | BTK INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2024-11-06 | — | — | EP | disclosed |
| EP-3630770-B1 | PYRAZOLO[3,4-B]PYRAZINE DERIVATIVES AS SHP2 PHOSPHATASE INHIBITORS | RELAY THERAPEUTICS INC (US) | 2024-08-28 | — | — | EP | disclosed |
| US-20230293569-A1 | MODULATING NUDIX HOMOLOGY DOMAIN (NHD) WITH NICOTINAMIDE MONONUCLEOTIDE ANALOGS AND DERIVATIVES OF SAME | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2023-09-21 | — | — | US | disclosed |
| US-20230242565-A1 | Macrolides with Modified Desosamine Sugars and Uses Thereof | ZIKANI THERAPEUTICS, INC. | 2023-08-03 | — | — | US | disclosed |
| US-20230242565-A1 | Macrolides with Modified Desosamine Sugars and Uses Thereof | ZIKANI THERAPEUTICS, INC. | 2023-08-03 | — | — | US | disclosed |
| CN-116332910-A | 2-aminopyrimidine derivatives as kinase inhibitors, preparation and use thereof | 江苏威凯尔医药科技有限公司 | 2023-06-27 | — | — | CN | disclosed |
| US-11673910-B2 | Macrolides with modified desosamine sugars and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2023-06-13 | — | — | US | disclosed |
| US-11673910-B2 | Macrolides with modified desosamine sugars and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2023-06-13 | — | — | US | disclosed |
| US-20230158053-A1 | NICOTINAMIDE MONONUCLEOTIDE DERIVATIVES AND THEIR USES | METROBIOTECH, LLC | 2023-05-25 | — | — | US | disclosed |
| US-20230158053-A1 | NICOTINAMIDE MONONUCLEOTIDE DERIVATIVES AND THEIR USES | METROBIOTECH, LLC | 2023-05-25 | — | — | US | disclosed |
| EP-0738155-A1 | MODULAR DESIGN AND SYNTHESIS OF OXAZOLONE-DERIVED MOLECULES | ARQULE, INC. (US) | 1996-10-23 | — | — | EP | disclosed |
| EP-0724446-A1 | ELECTROPHILIC PEPTIDE ANALOGS AS INHIBITORS OF TRYPSIN-LIKE ENZYMES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-08-07 | — | — | EP | disclosed |
| EP-0649443-A4 | OXAZOLONE DERIVED MATERIALS. | LEGOMER PARTNERS LP (US) | 1995-11-08 | — | — | EP | disclosed |
| CN-1105353-A | Modular design and synthesis of oxazolone-derived molecules | ARQULE PARTNERS L P (US) | 1995-07-19 | — | — | CN | disclosed |
| WO-1995017903-A1 | MODULAR DESIGN AND SYNTHESIS OF OXAZOLONE-DERIVED MOLECULES | ARQULE PARTNERS, L.P. (US) | 1995-07-06 | — | — | WO | disclosed |
| EP-0649443-A1 | OXAZOLONE DERIVED MATERIALS | LEGOMER PARTNERS, L.P. (US) | 1995-04-26 | — | — | EP | disclosed |
| WO-1995009634-A1 | ELECTROPHILIC PEPTIDE ANALOGS AS INHIBITORS OF TRYPSIN-LIKE ENZYMES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-04-13 | — | — | WO | disclosed |
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |
| WO-1994000509-A9 | OXAZOLONE DERIVED MATERIALS | — | 1994-03-17 | — | — | WO | disclosed |
| WO-1994000509-A1 | OXAZOLONE DERIVED MATERIALS | LEGOMER PARTNERS, L.P. (US) | 1994-01-06 | — | — | WO | disclosed |