Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTR1B | P28222 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10425437 | 0.85 | POLB (0.54) | POLBMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL10500417 | 0.85 | TDP1 (0.55) | ALDH1A1CYP1A2L3MBTL1TUBB4ATUBB | |
| SCHEMBL28875517 | 0.84 | TDP1 (0.54) | ALDH1A1CYP1A2L3MBTL1TUBB4ATUBB | |
| SCHEMBL1750794 | 0.84 | POLB (0.53) | POLBMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL30932948 | 0.82 | POLB (0.51) | POLBMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL18076011 | 0.82 | POLB (0.51) | POLBMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL10610842 | 0.81 | POLB (0.50) | POLBMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL27942332 | 0.81 | MEN1 (0.50) | POLBMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL8463126 | 0.79 | POLB (0.56) | POLBMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL7221502 | 0.79 | SMN1; SMN2 (0.61) | MEN1KMT2AALDH1A1CYP3A4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016147133-A1 | PROCESS FOR THE PREPARATION OF DROXIDOPA | Piramal Enterprises Limited (IN) | 2016-09-22 | — | — | WO | disclosed |
| US-20160251320-A1 | Compounds | UNIVERSITÉ CLAUDE BERNARD LYON 1 (FR) | 2016-09-01 | — | — | US | disclosed |
| EP-1487928-B1 | FILM-FORMING POLYMER AND ANTIFOULING PAINT | JOTUN AS (NO) | 2008-08-13 | — | — | EP | disclosed |
| CN-1643085-A | Film-forming polymer and antifouling paint | JOTUN AS (NO) | 2005-07-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160251320-A1 | Compounds | NISCH, MDN1, PIR | POLB 903/4885MEN1 4/4885KMT2A 4253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.