SCHEMBL4644515

SCHEMBL4644515

[CH2]C(=O)Oc1ccc(OC)cc1C=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.57
ERN1 O75460 3/20 0.56
TRIM24 O15164 1/20 0.51
TYR P14679 1/20 0.51
TRIM33 Q9UPN9 1/20 0.51
KDM4E B2RXH2 2/20 0.50
JUN P05412 1/20 0.50
NFKB1 P19838 1/20 0.50
RAB9A P51151 1/20 0.50
ABCG2 Q9UNQ0 1/20 0.47
CYP1A2 P05177 3/20 0.45
CYP2C19 P33261 2/20 0.45
LMNA P02545 1/20 0.45
CYP2C9 P11712 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
PDE4A P27815 1/20 0.44
PDE4B Q07343 1/20 0.44
PDE4C Q08493 1/20 0.44
PDE4D Q08499 1/20 0.44
TUBB1 Q9H4B7 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16112011 0.87 ALDH1A1 (0.61) ALDH1A1ERN1TRIM24TYRTRIM33
SCHEMBL4644522 0.85 ALDH1A1 (0.59) ALDH1A1ERN1TRIM24TYRTRIM33
SCHEMBL16045979 0.85 ALDH1A1 (0.59) ALDH1A1ERN1TRIM24TYRTRIM33
SCHEMBL1665643 0.84 ALDH1A1 (0.57) ALDH1A1ERN1TRIM24TYRTRIM33
SCHEMBL4645654 0.83 KDM4E (0.53) ALDH1A1ERN1TRIM24TYRTRIM33
SCHEMBL4645650 0.83 ALDH1A1 (0.56) ALDH1A1ERN1TRIM24TYRTRIM33
SCHEMBL4642070 0.81 KDM4E (0.54) ALDH1A1ERN1TRIM24TYRTRIM33
SCHEMBL1667861 0.81 ALDH1A1 (0.54) ALDH1A1ERN1TRIM24TYRTRIM33
SCHEMBL4642357 0.81 KDM4E (0.51) ALDH1A1ERN1TRIM24TYRTRIM33
SCHEMBL29392394 0.81 ALDH1A1 (0.71) ALDH1A1ERN1TRIM24TYRTRIM33

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed